Spots Global Cancer Trial Database for Oncolytic Virus Ad-TD-nsIL12 for Progressive Pediatric Diffuse Intrinsic Pontine Glioma
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Trial Identification
Brief Title: Oncolytic Virus Ad-TD-nsIL12 for Progressive Pediatric Diffuse Intrinsic Pontine Glioma
Official Title: Oncolytic Virus Ad-TD-nsIL12 for Progressive Pediatric Diffuse Intrinsic Pontine Glioma
Study ID: NCT05717699
Interventions
Study Description
Brief Summary: This is a single-arm, single-center, drug safety assessment clinical trial with a 3+3 dose escalation design, to observe the safety, tolerability and toxicity of a novel oncolytic virus Ad-TD-nsIL12 intratumoral injection in progressive DIPG patients (NCI-CTCAE V5.0).
Detailed Description:
Keywords
Eligibility
Minimum Age: 1 Year
Eligible Ages: CHILD, ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Sanbo Brain Hospital, Capital Medical University, Beijing, Beijing, China
Contact Details
Name: Hongwei Zhang, Prof.
Affiliation: Capital Medical University
Role: PRINCIPAL_INVESTIGATOR
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