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Brief Title: Opioid Free Anesthesia in Breast Cancer Surgery
Official Title: Opioid Free Anesthesia in Breast Cancer Surgery: a Prospective Randomized Study
Study ID: NCT04390698
Brief Summary: A comparison of incidences of postoperative nausea and vomiting (PONV) , postoperative pain severity and recovery parameters in breast cancer patients receiving opioid or opioid-free general anesthesia.
Detailed Description: Breast cancer is one of the most common oncologic diagnosis in women. Surgery is traditionally performed under general anesthesia with opioid-based analgesia. It is associated with higher incidences of PONV, more severe acute postoperative pain and increased incidences of chronic pain. The possibility of higher risk of metastasis has also been reported. The purpose of our study is to compare the opioid-free general anesthesia with the opioid-based general anesthesia with respect to the quality of recovery, postoperative pain and cancer recurrence and metastasis.
Minimum Age: 20 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Peking University People's Hospital, Beijing, Beijing, China
Name: Yi Feng, MD,PhD
Affiliation: Peking University People's Hospital
Role: PRINCIPAL_INVESTIGATOR