Spots Global Cancer Trial Database for Trial of Individualized Adaptive RT in HPV-related High Risk Oropharynx Cancer
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Trial Identification
Brief Title: Trial of Individualized Adaptive RT in HPV-related High Risk Oropharynx Cancer
Official Title: Pilot Phase II Trial of Individualized Adaptive RT in HPV-related High Risk Oropharynx Cancer
Study ID: NCT06234748
Study Description
Brief Summary: This study seeks to study the population of HPV-related oropharynx cancer patients that appear to be at highest risk for treatment failure with loco-regional failure and distant metastases including cT4 or cN3. The study team aims to determine if it is feasible to use multi-modality imaging (both DCE MRI and FDG-PET) to optimize the radiation boost in high risk p16+ OPSCC with similar or decreased toxicity compared to historic standard therapy.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
University of Michigan Rogel Cancer Center, Ann Arbor, Michigan, United States
Contact Details
Name: Michelle Mierzwa
Affiliation: University of Michigan Rogel Cancer Center
Role: PRINCIPAL_INVESTIGATOR
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