Spots Global Cancer Trial Database for Genetic Biomarkers in Tissue Samples From Patients With Osteosarcoma
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Trial Identification
Brief Title: Genetic Biomarkers in Tissue Samples From Patients With Osteosarcoma
Official Title: Observational - Gene Discovery in Osteosarcoma
Study ID: NCT01807143
Conditions
Interventions
Study Description
Brief Summary: This clinical trial studies genetic biomarkers in tissue samples from patients with osteosarcoma. Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer
Detailed Description: Study Subtype: Ancillary/Correlative Observational Study Model: Cohort Time Perspective: Retrospective Biospecimen Retention: Samples With DNA Biospecimen Description: Tissue Study Population Description: Samples from the COG Sampling Method: Non-Probability Sample PRIMARY OBJECTIVES: I. To use PET sequencing to analyze DNA from ten human primary osteosarcoma samples, along with matched normal tissue where available. OUTLINE: Tissue samples are analyzed for translocations and deletions and analyzed using polymerase chain reaction (PCR) or fluorescence in situ hybridization (FISH).
Keywords
Eligibility
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Children's Oncology Group, Monrovia, California, United States
Contact Details
Name: Richard Gorlick, MD
Affiliation: Children's Oncology Group
Role: PRINCIPAL_INVESTIGATOR
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