Spots Global Cancer Trial Database for Patients Derived Organoids in Ovarian Cancer
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Trial Identification
Brief Title: Patients Derived Organoids in Ovarian Cancer
Official Title: Patients Derived Organoids (PDOs) Immune Cells Co-culture in Ovarian Cancer: the Role of TUmoR microEnvironment.
Study ID: NCT06085404
Conditions
Interventions
Study Description
Brief Summary: Among cancer models, patients derived organoids (PDOs) best reproduce tumor's tissue architecture, intratumor heterogeneity and are able to mimic in vivo patients' drugs response. For these reasons, it has been designed a study to assess the feasibility of PDOs immune cells co-culture in OC patients and the concordance between ex vivo sensitivity and in vivo treatment response. If proven effective and reliable, PDOs could be introduced into clinical practice as empirical predictor of patients' response to antineoplastic drugs.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
Policlinico Universitario Agostino Gemelli, Roma, , Italy
Contact Details
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