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Spots Global Cancer Trial Database for Study of XL999 in Patients With Previously Treated Ovarian Cancer

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Trial Identification

Brief Title: Study of XL999 in Patients With Previously Treated Ovarian Cancer

Official Title: A Phase 2 Study of XL999 Administered Intravenously to Subjects With Recurrent Ovarian Cancer

Study ID: NCT00277290

Conditions

Ovarian Cancer

Interventions

XL999

Study Description

Brief Summary: This clinical trial is being conducted at multiple sites to evaluate the activity, safety, and tolerability of XL999 when given weekly to patients with ovarian cancer that has previously been treated with platinum-based chemotherapy. XL999 is a small molecule inhibitor of multiple kinases including VEGFR, PDGFR, FGFR, FLT-3, and Src, which are involved in tumor cell growth, formation of new blood vessels (angiogenesis), and metastasis.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: FEMALE

Healthy Volunteers: No

Locations

California Cancer Care, Inc., Greenbrae, California, United States

Hematology/Oncology Associates of the Treasure Coast, Port St. Lucie, Florida, United States

University of Chicago, Chicago, Illinois, United States

Joliet Oncology-Hematology Associates, Ltd, Joliet, Illinois, United States

Indiana University Cancer Center, Indianapolis, Indiana, United States

Harry and Jeanette Weinberg Cancer Institute at Franklin Square, Baltimore, Maryland, United States

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

Bradley Cohen, New City, New York, United States

Memorial Sloan-Kettering Cancer Center, New York, New York, United States

Contact Details

Name: Lynne A. Bui, MD

Affiliation: Exelixis

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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