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Spots Global Cancer Trial Database for A Study Evaluating the Efficacy and Safety of Biomarker-Driven Therapies in Patients With Persistent or Recurrent Rare Epithelial Ovarian Tumors

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Trial Identification

Brief Title: A Study Evaluating the Efficacy and Safety of Biomarker-Driven Therapies in Patients With Persistent or Recurrent Rare Epithelial Ovarian Tumors

Official Title: A Phase II, Open-Label, Multicenter, Platform Study Evaluating the Efficacy and Safety of Biomarker-Driven Therapies in Patients With Persistent or Recurrent Rare Epithelial Ovarian Tumors

Study ID: NCT04931342

Conditions

Ovarian Cancer

Study Description

Brief Summary: This study will evaluate the efficacy and safety of multiple biomarker-selected treatments in patients with persistent or recurrent rare epithelial ovarian, fallopian tube, or primary peritoneal tumors. Enrollment will take place in two phases: a preliminary phase followed by a potential expansion phase.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: FEMALE

Healthy Volunteers: No

Locations

Arizona Oncology - HOPE Wilmot, Tucson, Arizona, United States

Kaiser Permanente - Irvine, Irvine, California, United States

UCSF Helen Diller Family CCC, San Francisco, California, United States

Minnesota Oncology Hematology, Saint Paul, Minnesota, United States

Washington University School of Medicine; Dept of Medicine/Div of Medical Oncology, Saint Louis, Missouri, United States

Memorial Sloan Kettering Cancer Center, New York, New York, United States

Levine Cancer Institute, Charlotte, North Carolina, United States

Ohio State University, Columbus, Ohio, United States

University of Oklahoma Health Sciences Center; Stephenson Cancer Center, Oklahoma City, Oklahoma, United States

Northwest Cancer Specialists, P.C., Tigard, Oregon, United States

MD Anderson Cancer Center, Houston, Texas, United States

Texas Oncology - Gulf Coast, The Woodlands, Texas, United States

Huntsman Cancer Institute, Salt Lake City, Utah, United States

Virginia Oncology Associates, Norfolk, Virginia, United States

University of Washington - Seattle Cancer Care Alliance; Medical Oncology, Seattle, Washington, United States

Cabrini Hospital; Cabrini Foundation, Malvern, Victoria, Australia

Princess Margaret Cancer Center, Toronto, Ontario, Canada

McGill University Health Centre - Glen Site, Montreal, Quebec, Canada

Fakultni nemocnice Brno Bohunice, Brno, , Czechia

Gynekologicko-porodnicka klinika, Prague, , Czechia

CHU Besançon - Hôpital Jean Minjoz, Besançon Cedex, , France

Institut Bergonie; Oncologie, Bordeaux, , France

Centre Francois Baclesse; Oncologie, Caen, , France

CENTRE LEON BERARD; Département d?Hématologie et d?Oncologie, Lyon, , France

Institut Régional du Cancer de Montpellier, Montpellier, , France

Groupe Hospitalier Diaconesses, Paris, , France

Centre Eugène Marquis, Rennes, , France

ICO - Site René Gauducheau, Saint Herblain, , France

Institut Claudius Regaud; Departement Oncologie Medicale, Toulouse, , France

Gustave Roussy, Villejuif, , France

Campus Virchow-Klinikum Charité; Centrum 17; Klinik für Gynäkologie, Berlin, , Germany

Universitätsklinikum "Carl Gustav Carus"; Frauenheilkunde und Geburtshilfe, Dresden, , Germany

Kliniken Essen-Mitte Evang. Huyssens-Stiftung, Klinik für Gynäkologie und gynäkologische Onkologie, Essen, , Germany

Universitätsklinikum Mannheim; Frauenklinik, Mannheim, , Germany

Klinikum der Universität München; Campus Großhadern; Klinik und Poliklinik für Frauenheilkunde, Muenchen, , Germany

Istituto Tumori Napoli;Unità Operativa Oncologia Medica Uro-Ginecologica, Napoli, Campania, Italy

Policlinico Universitario Agostino Gemelli, Roma, Lazio, Italy

IRCCS S. Raffaele; Ginecologia Oncologica, Milano, Lombardia, Italy

Irccs Istituto Europeo Di Oncologia (IEO); Oncologia Medica, Milano, Lombardia, Italy

I.R.C.C. Candiolo; Oncologia Medica e Ematologia, Candiolo, Piemonte, Italy

A.O. U. Consorziale Policlinico di Bari; Oncologia Ginecologica, Bari, Puglia, Italy

Seoul National University Hospital, Seoul, , Korea, Republic of

Severance Hospital, Yonsei University Health System, Seoul, , Korea, Republic of

Asan Medical Center, Seoul, , Korea, Republic of

Samsung Medical Center, Seoul, , Korea, Republic of

LLC Medscan, Moskva, Moskovskaja Oblast, Russian Federation

FSBI "Federal Medical Research Center n.a. V.A.Almazov", Sankt-peterburg, Sankt Petersburg, Russian Federation

Chelyabisnk regional clinical center for oncology and nuclear medicine, Chelyabinsk, Sverdlovsk, Russian Federation

Institutio Catalan De Oncologia, Badalona, Barcelona, Spain

Hospital Universitario 12 de Octubre; Servicio de Oncologia, Madrid, , Spain

Hospital Universitario La Paz; Servicio de Oncologia, Madrid, , Spain

Hospital Clinico Universitario Virgen de la Victoria; Servicio de Oncologia, Malaga, , Spain

Hôpitaux Universitaires de Genève; Département d'oncologie, Genève, , Switzerland

Adana Baskent University Medical Faculty; Oncology, Adana, , Turkey

Baskent Universitesi Ankara Hastanesi; Tıbbi Onkoloji Bölümü, Ankara, , Turkey

Koc University Medical Faculty; Department of Gynecology & Obstetrics, Istanbul, , Turkey

Western General Hospital; Edinburgh Cancer Center, Edinburgh, , United Kingdom

University College London Hospitals NHS Foundation Trust - University College Hospital, London, , United Kingdom

Contact Details

Name: Clinical Trials

Affiliation: Hoffmann-La Roche

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

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