Spots Global Cancer Trial Database for Use of ACA 125 in Patients With Ovarian Cancer: Safety and Immune Response
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Trial Identification
Brief Title: Use of ACA 125 in Patients With Ovarian Cancer: Safety and Immune Response
Official Title: A Phase I/II Trial of ACA 125 in Patients With Recurrent Epithelial Ovarian, Fallopian Tube or Peritoneal Cancer
Study ID: NCT00103545
Interventions
Study Description
Brief Summary: The purpose of this study is to use an immunologic approach following the treatment for recurrent disease in patients with ovarian, fallopian tube, or peritoneal cancer.
Detailed Description: Patients with epithelial ovarian, fallopian tube or peritoneal cancer who receive surgical cytoreduction and platinum/taxane containing chemotherapy have a significant chance of entering complete clinical remission but about 70% will eventually relapse. Many patients respond to additional cytotoxic treatment with partial or complete responses, yet approximately 100% of these patients will ultimately progress. Novel consolidation strategies following treatment for recurrent disease are needed and an immunologic approach is an attractive option.
Eligibility
Minimum Age: 0 Years
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
Clinic for Gynecology and Gyn. Oncology, Humboldt University, Berlin, , Germany
University Clinic Carl Gustav Carus, Gynecological hospital, Dresden, , Germany
Gynecologic Hospital, Duesseldorf, , Germany
University Gynecologic Hospital, Essen, , Germany
University Gynecologic Hospital, Frankfurt, , Germany
Gynecologic Clinic of the Ernst-Moritz-Arndt-University, Greifswald, , Germany
University Clinic Schleswig-Holstein, Campus Kiel, Clinic for gynecology and obstetrics, Kiel, , Germany
Otto-von-Guericke University, University Gynecological Hospital, Magdeburg, , Germany
Clinic of the Philipps University Marburg, Clinic for gynecology, gyn. endocrinology and oncology, Marburg, , Germany
University Gynecological Hospital, Ulm, , Germany
Clinic for Gnyecology and gyn. Oncology HSK, Wiesbaden, , Germany
Contact Details
Name: Jacobus Pfisterer, Prof. Dr.
Affiliation: AGO Study Group
Role: PRINCIPAL_INVESTIGATOR
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