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Brief Title: A Phase 2 Study of the IDO Inhibitor Epacadostat Versus Tamoxifen for Subjects With Biochemical-recurrent-only EOC, PPC or FTC Following Complete Remission With First-line Chemotherapy
Official Title: A Randomized, Open-Label, Phase 2 Study of the IDO Inhibitor Epacadostat Versus Tamoxifen for Subjects With Biochemical-Recurrent-Only Epithelial Ovarian Cancer, Primary Peritoneal Carcinoma, or Fallopian Tube Cancer Following Complete Remission With First-Line Chemotherapy
Study ID: NCT01685255
Brief Summary: This is an open-label, randomized, phase 2 study of an IDO inhibitor, INCB024360 (epacadostat) versus tamoxifen in biochemical recurrent only ovarian cancer patients following complete remission with first-line chemotherapy.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
, La Jolla, California, United States
, Los Angeles, California, United States
, San Francisco, California, United States
, Evanston, Illinois, United States
, Joliet, Illinois, United States
, Iowa City, Iowa, United States
, Covington, Louisiana, United States
, Baltimore, Maryland, United States
, Detroit, Michigan, United States
, Minneapolis, Minnesota, United States
, Bridgewater, New York, United States
, Buffalo, New York, United States
, Mineola, New York, United States
, Durham, North Carolina, United States
, Abington, Pennsylvania, United States
, Philadelphia, Pennsylvania, United States
, Greenville, South Carolina, United States
, Bendigo, , Australia
, Heidelberg, , Australia
, Herston, , Australia
, Milton, , Australia
, Randwick, , Australia
, Calgary, Alberta, Canada
, Toronto, Ontario, Canada
, Montreal, Quebec, Canada
, Ekaterinburg, , Russian Federation
, Izhevsk, , Russian Federation
, Krasnodar, , Russian Federation
, Kursk, , Russian Federation
, Moscow, , Russian Federation
, Orenburg, , Russian Federation
, St. Petersburg, , Russian Federation
, Ufa, , Russian Federation
, Chernivtsi, , Ukraine
, Dnepropetrovsk, , Ukraine
, Kharkiv, , Ukraine
, Lutsk, , Ukraine
, Bebington, , United Kingdom
, Cardiff, , United Kingdom
, Edinburgh, , United Kingdom
, Glasgow, , United Kingdom
, Keighley, , United Kingdom
, Leeds, , United Kingdom
, Liverpool, , United Kingdom
, London, , United Kingdom
, Manchester, , United Kingdom
, Nottingham, , United Kingdom
, Oxford, , United Kingdom
, West Midlands, , United Kingdom
Name: Lance Leopold, M.D.
Affiliation: Incyte Corporation
Role: STUDY_DIRECTOR