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Spots Global Cancer Trial Database for Platine, Avastin and OLAparib in 1st Line

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Trial Identification

Brief Title: Platine, Avastin and OLAparib in 1st Line

Official Title: Randomized, Double-Blind, Phase III Trial Olaparib vs. Placebo Patients With Advanced FIGO Stage IIIB-IV High Grade Serious or Endometrioid Ovarian, Fallopian Tube, or Peritoneal Cancer Treated Standard First-Line Treatment

Study ID: NCT02477644

Conditions

Ovarian Cancer

Interventions

Olaparib
Placebo

Study Description

Brief Summary: Randomized, Double-Blind, Phase III Trial of Olaparib vs. Placebo in Patients with Advanced FIGO Stage IIIB - IV High Grade Serous or Endometrioid Ovarian, Fallopian Tube, or Peritoneal Cancer treated with standard First-Line Treatment, Combining Platinum-Taxane Chemotherapy and Bevacizumab Concurrent with Chemotherapy and in Maintenance.

Detailed Description: Patients with advanced FIGO stage IIIB - IV high grade serous or endometrioid ovarian, fallopian tube, or peritoneal cancer treated with standard first-line treatment, combining platinum-taxane chemotherapy and bevacizumab concurrent with chemotherapy and in maintenance.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: FEMALE

Healthy Volunteers: No

Locations

KH der Barmherzigen Brüder Graz, Graz, , Austria

Medical University of Graz, Graz, , Austria

Medical University of Innsbruck, Innsbruck, , Austria

Landeskrankenhaus Salzburg, Salzburg, , Austria

Medical University of Vienna, Vienna, , Austria

Krankenhaus Hietzing, Vienna, , Austria

Institut Jules Bordet, Bruxelles, , Belgium

Antwerp University Hospital, Edegem, , Belgium

UZ Gasthuisberg, Leuven, , Belgium

Hôpital de la Citadelle, Liège, , Belgium

Clinique et maternité Sainte Elisabeth, Namur, , Belgium

CHU Dinant Godinne, Yvoir, , Belgium

Rigshospitalet, Copenhagen, , Denmark

Herlev Hospital, Herlev, , Denmark

Kuopio University Hospital, Kuopio, , Finland

Oulu University Hospital, Oulu, , Finland

Tampere University Hospital, Tampere, , Finland

Turku University Hospital, Turku, , Finland

Hôpital Européen Georges Pompidou, Paris, Ilhe De France, France

ICO Paul Papin, Angers, , France

Institut Sainte-Catherine, Avignon, , France

Hôpital Jean Minjoz, Besancon, , France

Institut Bergonié, Bordeaux, , France

Polyclinique Bordeaux Nord, Bordeaux, , France

Centre François Baclesse, Caen, , France

Centre Jean Perrin, Clermont-ferrand, , France

Centre Georges François Leclerc, Dijon, , France

Groupe Hospitalier Mutualiste de Grenoble, Grenoble, , France

Centre Hospitalier Départemental Les Oudairies, La Roche-sur-yon, , France

Hôpital Michallon - Centre Hospitalier Universitaire de Grenoble, La Tronche, , France

Centre Jean Bernard - Clinique Victor Hugo, Le Mans, , France

Centre Hospitalier Régional Universitaire de Lille - Hôpital Huriez, Lille, , France

Centre Oscar Lambret, Lille, , France

Centre Léon Bérard, Lyon, , France

Institut Paoli Calmettes, Marseille, , France

Hôpital de Mont-de-Marsan, Mont-de-marsan, , France

ICM Val d'Aurelle, Montpellier, , France

Centre Azuréen de Cancérologie, Mougins, , France

Centre Catherine de Sienne - Group confluent, Nantes, , France

Centre Antoine Lacassagne, Nice, , France

Centre Hospitalier Régional d'Orléans, Orleans, , France

Institut Curie - Hopital Claudius Régaud, Paris, , France

Hôpital des Diaconesses, Paris, , France

Hôpital Cochin, Paris, , France

Hopital Tenon, Paris, , France

Groupe Hospitalier Saint-Joseph, Paris, , France

Clinique Francheville, Perigueux, , France

Centre Hospitalier Lyon Sud, Pierre-benite, , France

Centre CARIO - HPCA, Plérin, , France

Hôpital de la Milétrie - CHU de Poitiers - Pôle Régional de Cancérologie, Poitiers, , France

Centre Eugène Marquis, Rennes, , France

Centre Henri Becquerel, Rouen, , France

Hôpital René Huguenin, Institut Curie, Saint-cloud, , France

ICO Centre René Gauducheau, Saint-herblain, , France

Centre de Radiothérapie - Clinique Sainte-Anne, Strasbourg, , France

Centre Paul Strauss, Strasbourg, , France

Hôpitaux Universitaires de Strasbourg, Strasbourg, , France

Institut Claudius Regaud, Toulouse, , France

Clinique Pasteur - ONCOSUD, Toulouse, , France

ICL Institut de Cancérologie de Lorraine, Vandoeuvre-les-nancy, , France

Institut Gustave Roussy, Villejuif, , France

Klinikum Aschaffenburg, Aschaffenburg, , Germany

Klinikum Augsburg, Augsburg, , Germany

Hochtaunus-Kliniken, Bad Homburg, , Germany

Praxisklinik Krebsheilkunde für Frauen, Berlin, , Germany

HELIOS Klinikum Berlin-Buch, Berlin, , Germany

Charité - Universitätsmedizin Berlin (CVK), Berlin, , Germany

Onkologie Bottrop, Bottrop, , Germany

GYNAEKOLOGICUM Bremen, Bremen, , Germany

Städtisches Klinikum Dessau, Dessau, , Germany

Universitätsklinikum Carl Gustav Carus, Dresden, , Germany

Evangelisches Krankenhaus Düsseldorf, Düsseldorf, , Germany

Universitätsklinikum Düsseldorf, Düsseldorf, , Germany

Universitätsfrauenklinik Erlangen, Erlangen, , Germany

Kliniken Essen Mitte, Essen, , Germany

Universitätsklinikum Essen, Essen, , Germany

Klinikum Esslingen, Esslingen, , Germany

Klinikum der Johann Wolfgang Goethe-Universität, Frankfurt, , Germany

Klinikum Frankfurt Höchst, Frankfurt, , Germany

Universitätsfrauenklinik Freiburg, Freiburg, , Germany

Universitätsmedizin Greifswald, Greifswald, , Germany

Universitäts-Frauenklinik Göttingen, Göttingen, , Germany

Klinkum Gütersloh, Gütersloh, , Germany

Universitätsklinikum Halle, Halle, , Germany

Universitätsklinikum Hamburg-Eppendorf, Hamburg, , Germany

Albertinen Krankenhaus, Hamburg, , Germany

Gynäkologisch-Onkologische Praxis Hannover, Hannover, , Germany

Medizinische Hochschule Hannover, Hannover, , Germany

Universitätsklinikum Heidelberg, Heidelberg, , Germany

Universitätsklinikum Jena, Jena, , Germany

St. Vincentius Kliniken, Karlsruhe, , Germany

Klinikum Kassel, Kassel, , Germany

Universitätsklinikum Schleswig-Holstein, Kiel, , Germany

Klinikum Konstanz, Konstanz, , Germany

HELIOS Klinikum Krefeld, Krefeld, , Germany

Universitätsfrauenklinik Köln, Köln, , Germany

St. Elisabeth Krankenhaus, Köln, , Germany

Klinikum Ludwigsburg, Ludwigsburg, , Germany

Universitätsklinikum Schleswig-Holstein, Lübeck, , Germany

Universitätsklinikum Gießen und Marburg, Marburg, , Germany

Johannes Wesling Klinikum, Minden, , Germany

Klinikum der Universität München, München, , Germany

Klinikum rechts der Isar, München, , Germany

Universitätsklinikum Münster, Münster, , Germany

Kliniken des Landkreises Neumarkt, Neumarkt, , Germany

Sana Klinikum Offenbach, Offenbach, , Germany

Ortenau Klinikum, Offenburg, , Germany

Onkologie Ravensburg, Ravensburg, , Germany

Universitätsfrauenklinik Regensburg, Regensburg, , Germany

Klinikum am Steinenberg, Reutlingen, , Germany

ROMed Klinikum Rosenheim, Rosenheim, , Germany

Klinikum Südstadt, Rostock, , Germany

Robert-Bosch-Krankenhaus, Stuttgart, , Germany

Universitäts-Frauenklinik Tübingen, Tübingen, , Germany

Universitätsklinikum Ulm, Ulm, , Germany

HELIOS Dr. Horst Schmidt Kliniken, Wiesbaden, , Germany

Marien Hospital Witten, Witten, , Germany

amO Wolfsburg, Wolfsburg, , Germany

Klinikum Worms, Worms, , Germany

Universitätsklinikum Würzburg, Würzburg, , Germany

Centro Riferimento Oncologico, Aviano, , Italy

Policlinico S.Orsola-Malpighi, Bologna, , Italy

Spedali Civili-Università di Brescia, Brescia, , Italy

Ospedale Senatore Antonio Perrino, Brindisi, , Italy

EO Ospedali Galliera, Genova, , Italy

Ospedale San Luca, Lucca, , Italy

Istituto Nazionale Tumori, Milano, , Italy

Istituto Europeo di Oncologia, Milano, , Italy

Istituto Nazionale Tumori - IRCCS Pascale, Napoli, , Italy

Istituto Oncologico Veneto, Padova, , Italy

Ospedale Santa Maria della Misericordia, Perugia, , Italy

Ospedale Santa Chiara, Pisa, , Italy

AO ASL 4 - Ospedale di Prato, Prato, , Italy

Arcispedale S. M. Nuova, Reggio Emilia, , Italy

Istituto Regina Elena, Roma, , Italy

Policlinico Umberto I La Sapienza, Roma, , Italy

Policlinico Universitario Gemelli Università Cattolica del Sacro Cuore, Roma, , Italy

Ospedale S. Anna, Torino, , Italy

Ospedale Mauriziano, Torino, , Italy

Ospedale Santa Chiara, Trento, , Italy

Ehime University Hospital, Ehime, , Japan

Hyogo Cancer Center, Hyogo, , Japan

University of Tsukuba Hospital, Ibaraki, , Japan

Kagoshima University Medical And Dental Hospital, Kagoshima, , Japan

Saitama Medical University International Medical Center, Saitama, , Japan

Jichi Medical University Hospital, Tochigi, , Japan

National Cancer Center Hospital, Tokyo, , Japan

Centre Hospitalier Princesse Grace, Monaco, , Monaco

H. U. Fundación Alcorcón, Alcorcón, , Spain

H. de la Santa Creu i Sant Pau, Barcelona, , Spain

C.S. Parc Taulí, Barcelona, , Spain

H. U. Reina Sofía, Córdoba, , Spain

H.U. Arnau de Vilanova, Lleida, , Spain

MD Anderson Cancer Center Madrid, Madrid, , Spain

H. U. Ramón y Cajal, Madrid, , Spain

H. U. 12 de Octubre, Madrid, , Spain

H.U. Central de Asturias, Oviedo, , Spain

Complejo Hospitalario de Navarra, Pamplona, , Spain

H. General Universitario de Valencia, Valencia, , Spain

H. U. P. La Fe, Valencia, , Spain

Instituto Valenciano de Oncología, València, , Spain

H. U. Miguel Servet, Zaragoza, , Spain

Linköping University Hospital, Linköping, , Sweden

Contact Details

Name: Isabelle RAY COQUARD, MD, PhD

Affiliation: Centre Leon Berard

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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