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Brief Title: Study to Compare the Efficacy and Safety of Olaparib When Given in Combination With Carboplatin and Paclitaxel, Compared With Carboplatin and Paclitaxel in Patients With Advanced Ovarian Cancer
Official Title: A Phase II Open Label Randomised Comparative Multicentre Study to Compare the Efficacy and Tolerability of Olaparib in Combination With Paclitaxel and Carboplatin Versus Paclitaxel and Carboplatin Alone in Patients With Platinum Sensitive Advanced Serous Ovarian Cancer
Study ID: NCT01081951
Brief Summary: To compare the efficacy of olaparib in combination with paclitaxel and carboplatin (AUC4) when compared with carboplatin (AUC6) and paclitaxel alone in patients with advanced ovarian cancer.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Research Site, West Hollywood, California, United States
Research Site, Orlando, Florida, United States
Research Site, Boston, Massachusetts, United States
Research Site, New York, New York, United States
Research Site, Portland, Oregon, United States
Research Site, Parkville, , Australia
Research Site, Randwick, , Australia
Research Site, Brussels, , Belgium
Research Site, Leuven, , Belgium
Research Site, Namur, , Belgium
Research Site, Wilrijk, , Belgium
Research Site, Vancouver, British Columbia, Canada
Research Site, Hamilton, Ontario, Canada
Research Site, Toronto, Ontario, Canada
Research Site, Quebec, , Canada
Research Site, Brno, , Czechia
Research Site, Hradec Kralove, , Czechia
Research Site, Olomouc, , Czechia
Research Site, Essen, , Germany
Research Site, Frankfurt, , Germany
Research Site, Hamburg, , Germany
Research Site, München, , Germany
Research Site, Solingen, , Germany
Research Site, Genova, , Italy
Research Site, Milan, , Italy
Research Site, Monza, , Italy
Research Site, Torino, , Italy
Research Site, Chuo-ku, , Japan
Research Site, Fukuoka-shi, , Japan
Research Site, Matsuyama-shi, , Japan
Research Site, Morioka-shi, , Japan
Research Site, Shinjuku-ku, , Japan
Research Site, Yamagata-shi, , Japan
Research Site, Amsterdam, , Netherlands
Research Site, Nijmegen, , Netherlands
Research Site, Rotterdam, , Netherlands
Research Site, Lima, , Peru
Research Site, Lima, , Peru
Research Site, Madrid, , Spain
Research Site, Valencia, , Spain
Research Site, Birmingham, , United Kingdom
Research Site, Edinburgh, , United Kingdom
Name: Jane Robertson, BSc, MBCHB, MD
Affiliation: AstraZeneca
Role: STUDY_DIRECTOR
Name: Amit Oza, MD
Affiliation: Princess Margaret Hospital, Canada
Role: PRINCIPAL_INVESTIGATOR