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Brief Title: [18F]Fluciclatide-PET, Pazopanib and Paclitaxel in Ovarian Cancer
Official Title: Phase 1b Exploratory Study of [18F]Fluciclatide-PET as a Marker of Angiogenic Response to Combination Therapy With the Pan-VEGF Inhibitor, Pazopanib, and Weekly Paclitaxel in Platinum Resistant Ovarian Cancer
Study ID: NCT01608009
Brief Summary: The purpose of this study is to assess \[18F\] -fluciclatide as a biomarker of response to pazopanib and to evaluate the efficacy and safety of the combination of pazopanib and paclitaxel in platinum-resistant ovarian cancer patients.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Imperial College Healthcare NHS Trust, London, , United Kingdom
Southend University Hospital NHS Foundation Trust, Southend, , United Kingdom
Name: Rohini Sharma, MD
Affiliation: Imperial College London
Role: STUDY_DIRECTOR
Name: Timothy Crook, MD
Affiliation: Southend University Hospital NHS Foundation Trust
Role: PRINCIPAL_INVESTIGATOR