Spots Global Cancer Trial Database for A Study of LY4170156 in Participants With Selected Advanced Solid Tumors
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Trial Identification
Brief Title: A Study of LY4170156 in Participants With Selected Advanced Solid Tumors
Official Title: A First-in-Human, Phase 1a/1b Trial to Assess the Safety, Tolerability and Preliminary Efficacy of LY4170156, an Antibody-Drug Conjugate Targeting Folate Receptor α-Expressing Tumor Cells, in Participants With Selected Advanced Solid Tumors
Study ID: NCT06400472
Interventions
Study Description
Brief Summary: The purpose of this study is to find out whether the study drug, LY4170156, is safe, tolerable and effective in participants with advanced solid tumors. The study is conducted in two parts - phase Ia (dose-escalation, dose-optimization) and phase Ib (dose-expansion). The study will last up to approximately 4 years.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
South Texas Accelerated Research Therapeutics (START), Grand Rapids, Michigan, United States
Contact Details
Name: Emin Avsar
Affiliation: Loxo Oncology, Inc.
Role: STUDY_DIRECTOR
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