Spots Global Cancer Trial Database for Anti-programmed Cell Death-1 Ligand 1 (aPDL-1) Antibody Atezolizumab, Bevacizumab and Acetylsalicylic Acid in Recurrent Platinum Resistant Ovarian Cancer
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Trial Identification
Brief Title: Anti-programmed Cell Death-1 Ligand 1 (aPDL-1) Antibody Atezolizumab, Bevacizumab and Acetylsalicylic Acid in Recurrent Platinum Resistant Ovarian Cancer
Official Title: A Phase II Study of the Anti-PDL1 Antibody Atezolizumab, Bevacizumab and Acetylsalicylic Acid to Investigate Safety and Efficacy of This Combination in Recurrent Platinum-resistant Ovarian, Fallopian Tube or Primary Peritoneal Adenocarcinoma
Study ID: NCT02659384
Conditions
Study Description
Brief Summary: This is a randomized phase II study, aimed at evaluating the efficacy (through progression free survival at 6 months) and safety of 5 different treatments involving atezolizumab, bevacizumab and/or acetylsalicylic acid in advanced recurrent platinum-resistant ovarian cancer patients in order to select the optimal treatments for further development in Phase III.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
Assistance Publique - Hopitaux de Paris - Hopital Europeen Georges Pompidou, Paris, , France
Centre Hospitalier Privé Saint-Grégoire, Saint-Grégoire, , France
Academisch Medisch Centrum - Universiteit van Amsterdam, Amsterdam, , Netherlands
Leiden University Medical Centre, Leiden, , Netherlands
Radboudumc - Radboud University Medical Center Nijmegen, Nijmegen, , Netherlands
Institut Catala d'Oncologia - ICO Badalona - Hospital Germans Trias i Pujol (Institut Catala D'Oncologia), Badalona, , Spain
Hospital Universitario San Carlos, Madrid, , Spain
Centre Hospitalier Universitaire Vaudois - Lausanne, Lausanne, , Switzerland
Centre Hospitalier Universitaire Vaudois, Lausanne, , Switzerland
Guy's and St Thomas' NHS - Guy s and St Thomas' NHS - Guy's Hospital, London, , United Kingdom
Royal Marsden Hospital - Chelsea, London, London, , United Kingdom
Royal Marsden Hospital - Sutton, Surrey, Sutton, , United Kingdom
Contact Details
Name: Susana- Banerjee
Affiliation: Royal Marsden Hospital - UK
Role: STUDY_CHAIR
Name: George Coukos
Affiliation: Centre hospitalier universitaire vaudois, Lausanne
Role: STUDY_CHAIR
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