Spots Global Cancer Trial Database for Study of Adding AMG 479 to First Line Chemotherapy in Patients With Optimally Debulked Epithelial Ovarian Cancer
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Trial Identification
Brief Title: Study of Adding AMG 479 to First Line Chemotherapy in Patients With Optimally Debulked Epithelial Ovarian Cancer
Official Title: A Randomized, Double-blind, Placebo Controlled, Multi-center, Phase II Study of Adding AMG 479, a Fully Human Monoclonal Antibody Against Insulin-like Growth Factor Type 1 Receptor (IGF-1R) to First Line Chemotherapy in Patients With Optimally Debulked ( < 1 cm ) Epithelial Ovarian Cancer
Study ID: NCT00718523
Conditions
Study Description
Brief Summary: This study will determine the value of adding AMG 479 (fully human monoclonal antibody against IGF-1R) to paclitaxel and carboplatin first line chemotherapy in patients with optimally debulked (\<1 cm) FIGO stage III and IV (positive pleural cytology only) ovarian epithelial (including fallopian tube and primary peritoneal) carcinoma.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
Central Hematology Oncology Medical Group Inc., Alhambra, California, United States
Providence Saint Joseph Medical Center, Burbank, California, United States
St Jude Heritage Healthcare, Fullerton, California, United States
Wilshire Oncology Medical Group Inc, La Verne, California, United States
University of Southern California, Los Angeles, California, United States
Cedars-Sinai Medical Center, Los Angeles, California, United States
UCLA, Los Angeles, California, United States
North Valley Hematology/Oncology Medical Group, Northridge, California, United States
Ventura County Hematology-Oncology Specialists, Oxnard, California, United States
University of California San Francisco, San Francisco, California, United States
Central Coast Medical Oncology Corporation, santa Maria, California, United States
Yale University School of Medicine, New Haven, Connecticut, United States
Memorial Cancer Institute, Hollywood, Florida, United States
Florida Hospital Cancer Institute, Orlando, Florida, United States
Moffitt Cancer Center, Tampa, Florida, United States
Winship Cancer Institute Emory University School of Medicine, Atlanta, Georgia, United States
Hematology and Oncology Specialists, LLC, Metairie, Louisiana, United States
Mayo Clinic, Rochester, Minnesota, United States
Comprehensive Cancer Centers of Nevada, Henderson, Nevada, United States
Hope A Women's Cancer Center, Asheville, North Carolina, United States
Wake Forest University Baptist Medical Center, Winston-Salem, North Carolina, United States
The Toledo Hospital, Toledo, Ohio, United States
University of Toledo, Toledo, Ohio, United States
Cross Cancer Institute, Edmonton, Alberta, Canada
London Health Science Center, London, Ontario, Canada
CHUM Hopital Notre Dame, Montreal, Quebec, Canada
Jewish General Hospital, Montreal, Quebec, Canada
Centre Hospitalier Départemental Les Oudairies, La Roche Sur Yon, , France
Centre Léon Bérard, Lyon, , France
Clinique Hartmann, Neuilly Sur Seine, , France
Institut Curie, Paris, , France
Charite Campus Benjamin Franklin, Berlin, , Germany
University Hospital Charite, Berlin, , Germany
Universitat Bonn, Bonn, , Germany
Universitatsklinikum Erlangen, Erlangen, , Germany
Universitatsklinikum Hamburg Eppendorf, Hamburg, , Germany
Universitatsklinikum des Saarlandes, Homburg, , Germany
Klinikum Kassel, Kassel, , Germany
Rotkreuzkrankenhaus Munchen, Munich, , Germany
Universitats Frauenklinik Tubingen, Tubingen, , Germany
St Jame's Hospital, Dublin, , Ireland
Waterford Regional Hospital, Waterford, , Ireland
Meir Medical Center, Kfar-Saba, , Israel
Sheba Medical Center, Ramat Gan, , Israel
Kaplan Medical Center, Rehovot, , Israel
Sourasky Medical Center, Tel Aviv, , Israel
Asaf Harofe MC, Zrifin, , Israel
Hospital Clinic i Provincial, Barcelona, , Spain
Hospital Universitario de Guadalajara, Guadalajara, , Spain
Hospital Universitario de Tenerife, La Laguna, , Spain
Hospital U 12 de Octubre, Madrid, , Spain
Hospital Universitario Virgen Macarena de Sevilla, Sevilla, , Spain
Saint James's University Hospital, Leeds, , United Kingdom
University College London, London, , United Kingdom
Mount Vernon cancer centre, Northwood, , United Kingdom
Contact Details
Name: Gottfried E Konecny, MD
Affiliation: University of California, Los Angeles
Role: STUDY_CHAIR
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