Spots Global Cancer Trial Database for Preoperative Pain Control in Liver Surgery Patients
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Trial Identification
Brief Title: Preoperative Pain Control in Liver Surgery Patients
Official Title: A Randomized Placebo-Controlled Study of Whether Pre-operative Pregabalin 150 mg Will Improve Pain Control in Patients With Hepatocellular Carcinoma Undergoing Partial Hepatectomy
Study ID: NCT01923948
Study Description
Brief Summary: Pregabalin 150mg or placebo are administered 1 hour preoperatively in patients undergoing partial hepatectomy. Postoperatively, patients receive morphine as rescue analgesic. Morphine consumption in the first 48 hours is documented. Postoperative pain is measured by the visual analogue scale (VAS) score.
Detailed Description: Methods: In this Randomized Controlled Trial, patients undergoing partial hepatectomy will be administered a single pre-operative dose of Pregabalin or a placebo. Primary endpoints are as follows: * Post-operative analgesic requirements * Post-operative VAS scale (rated 0-10) * Complications * Post-operative antiemetic requirement * Length of stay
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Eastern Hepatobiliary Surgery Hospital, Shanghai, , China
Contact Details
Name: li ai jun, MD
Affiliation: Eastern Hepatobiliary Surgery Hospital, Second Military Medical University
Role: STUDY_CHAIR
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