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Spots Global Cancer Trial Database for Chronic Pain Following Thoracic Surgery

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Trial Identification

Brief Title: Chronic Pain Following Thoracic Surgery

Official Title: Study of Persistent Postsurgical Pain Following Thoracic Surgery in Patients With Pulmonary Malignancies

Study ID: NCT01144845

Interventions

Thoracic surgery

Study Description

Brief Summary: Pain that persists after the healing of a surgical wound has previously been described as an important, but often unrecognized clinical problem. Persistent postsurgical (chronic postoperative pain) is the consequence of either ongoing inflammation or more common neuropathic pain as a result of surgical damage to peripheral nerves. Previous studies have shown that chronic pain is a frequent and serious complication following thoracic surgery. However, the prevalence of chronic pain following both thoracoscopy and anterior thoracotomy in patients with pulmonary malignancies is poorly characterized and the impact of this pain on patients' lives remains unclear. Thus, this study aims to investigate the prevalence of chronic pain following thoracoscopy or anterior thoracotomy, and the severity and impact of persistent post-surgical pain on daily life. This study is working with several hypotheses: 1.) persistent postsurgical pain following lung cancer surgery is predominantly of neuropathic nature and the presence of neuropathic symptoms increases the severity of postsurgical pain and reduces the patient's quality of life, 2.) the prevalence of chronic pain is reduced over time, and 3.) less invasive thoracic surgical interventions reduces the risk of the development of chronic pain.

Detailed Description:

Eligibility

Minimum Age:

Eligible Ages: CHILD, ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Department of Cardiothoracic and Vascular surgery, Aarhus University Hospital, Skejby, Aarhus N, , Denmark

Contact Details

Name: Kasper Grosen, PhDS, MHScS, RN

Affiliation: Department of Cardiothoracic and Vascular surgery, Aarhus University Hospital, Skejby, Denmark

Role: PRINCIPAL_INVESTIGATOR

Name: Hans K Pilegaard, MD

Affiliation: Department of Cardiothoracic and Vascular surgery, Aarhus University Hospital, Skejby, Denmark

Role: STUDY_DIRECTOR

Name: Vibeke Hjortdal, MD, Professor, DMSc, PhD

Affiliation: Department of Cardiothoracic and Vascular surgery, Aarhus University Hospital, Skejby, Denmark

Role: STUDY_CHAIR

Name: Mogens P Jensen, MD, PhD

Affiliation: Department of Rheumatology, Aarhus University Hospital, Aarhus Hospital, Denmark

Role: STUDY_CHAIR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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