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Brief Title: Postoperative Analgesia Impact of Narcotic Free Anesthesia
Official Title: The Impact on Postoperative Pain of Substituting Opioids by Beta Blockers for Peroperative Hemodynamic Control in Patients Undergoing Mastectomy
Study ID: NCT01544959
Brief Summary: The first hypothesis of the study is that substituting fentanyl by esmolol and metoprolol during general anesthesia for patients undergoing mastectomy will result in less pain and less narcotic consumption in the recovery room. The investigators will also verify the impact of that substitution on nausea and vomiting, on the time spent in the recovery room and on chronic postsurgical pain (3 and 6 months). Finally, the investigators will see the impact on breast cancer recurrence 5 years after the surgery.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Quebec, Canada
Name: Etienne de Medicis, MD MSc
Affiliation: Centre de recherche du Centre hospitalier universitaire de Sherbrooke
Role: PRINCIPAL_INVESTIGATOR