Spots Global Cancer Trial Database for Pancreatic Cancer Early Detection Consortium
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Trial Identification
Brief Title: Pancreatic Cancer Early Detection Consortium
Official Title: Pancreatic Cancer Early Detection Consortium
Study ID: NCT04970056
Interventions
Study Description
Brief Summary: The purpose of the Pancreatic Cancer Early Detection (PRECEDE) Consortium is to conduct research on multiple aspects of early detection and prevention of pancreatic ductal adenocarcinoma (PDAC) by establishing a multisite cohort of individuals with family history of PDAC and/or individuals carrying pathogenic/likely pathogenic germline variants (PGVs) in genes linked to PDAC risk for longitudinal follow up.
Detailed Description: The main objective of the PRECEDE Consortium is to build a shared resource to drive research in critical areas necessary for early detection and prevention of PDAC. The PRECEDE Consortium is an observational prospective cohort study, with single or serial biosample collection (every 6-12 months) in defined high-risk groups. A standardized procedure for collection and processing of human blood for the PRECEDE Consortium will be applied to all blood samples collected as part of the study. Barcoded samples will be stored at the clinical centers, using the specific labels for the PRECEDE study and corresponding data will be entered into the study database. Clinical data and outcomes will be obtained from institutional databases or clinical records to correlate patient information with laboratory results from biospecimens obtained for research. Patients will be followed by their attending physician and receive the standard follow-up care after the procedure in which biospecimen was obtained. It is the intent that biospecimens will be made available to all consortium investigators.
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: Yes
Locations
Mayo Clinic Arizona, Phoenix, Arizona, United States
Honor Health Research Institute, Scottsdale, Arizona, United States
Providence Health and Services, Burbank, California, United States
City of Hope, Duarte, California, United States
UC San Diego Moores Cancer Center, La Jolla, California, United States
Cedars-Sinai Medical Center, Los Angeles, California, United States
UCLA Health, Los Angeles, California, United States
UC Irvine Health, Orange, California, United States
UC Davis, Sacramento, California, United States
University of California, San Francisco (UCSF), San Francisco, California, United States
Yale University, New Haven, Connecticut, United States
Mayo Clinic Jacksonville, Jacksonville, Florida, United States
University of Miami, Miami, Florida, United States
Moffitt Cancer Center, Tampa, Florida, United States
Emory University Hospital, Atlanta, Georgia, United States
Illinois CancerCare, Bloomington, Illinois, United States
University of Chicago Medicine, Chicago, Illinois, United States
NorthShore University HealthSystem, Evanston, Illinois, United States
Kansas University Medical Center, Kansas City, Kansas, United States
Massachusetts General Hospital, Boston, Massachusetts, United States
Umass Memorial Medical Center, Worcester, Massachusetts, United States
University of Michigan, Ann Arbor, Michigan, United States
Beaumont/Corewell Health, Royal Oak, Michigan, United States
University of Nebraska Medical Center, Omaha, Nebraska, United States
Hackensack Meridian Health, Hackensack, New Jersey, United States
Icahn School of Medicine At Mount Sinai, New York, New York, United States
Columbia University Irving Medical Center, New York, New York, United States
University of Rochester Medical Center, Rochester, New York, United States
The Ohio State University, Columbus, Ohio, United States
Oregon Health & Science University, Portland, Oregon, United States
University of Pennsylvania, Philadelphia, Pennsylvania, United States
Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States
University of Pittsburgh Medical Center (Upmc), Pittsburgh, Pennsylvania, United States
University of Tennessee Graduate School of Medicine, Knoxville, Tennessee, United States
The University of Texas Southwestern Medical Center, Dallas, Texas, United States
MD Anderson Center, Houston, Texas, United States
Intermountain Health, Saint George, Utah, United States
Huntsman Cancer Institute, Salt Lake City, Utah, United States
Inova Schar Cancer Institute, Fairfax, Virginia, United States
VCU Massey Cancer Center, Richmond, Virginia, United States
University of Washington, Seattle, Washington, United States
British Columbia Cancer Agency, Vancouver, British Columbia, Canada
Uhn Mount Sinai Hospital, Toronto, Ontario, Canada
McGill University Health Centre, Montreal, Quebec, Canada
Semmelweis University Department of Pancreatic Disorders, Budapest, , Hungary
Landspitali University Hospital, Reykjavík, , Iceland
Sheba Medical Center, Ramat Gan, , Israel
Azienda Ospedaliera Universitaria Integrata Verona, Verona, , Italy
National Cancer Center of Singapore, Singapore, , Singapore
Ramón y Cajal University Hospital, Madrid, , Spain
National Cheng Kung University Hospital (NCKUH), Tainan, Taiwan T.o.c., Taiwan
University of Liverpool, Liverpool, , United Kingdom
Contact Details
Name: Diane Simeone, MD
Affiliation: UC San Diego Moores Cancer Center
Role: STUDY_CHAIR
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