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Brief Title: Docetaxel Plus Oxaliplatin as Therapy in Patients With Pancreatic Cancer
Official Title: Phase II Study: Docetaxel Plus Oxaliplatin as Second-line Therapy in Patients With Advanced Metastatic Pancreatic Cancer
Study ID: NCT00690300
Brief Summary: The purpose of this study is to test a combination-therapy of oxaliplatin and docetaxel in patients with metastatic or locally advanced adenocarcinoma of the pancreas after failure of a palliative first line therapy.
Detailed Description: For years Fluorouracil was the established treatment for pancreatic cancer with median survival times up to 8 months. Since 1997 Gemcitabine is also a standard therapy with in comparison to Fluorouracil a significant better clinical benefit. But after progression of the disease under a palliative first-line therapy there is no established second line therapy for pancreatic cancer. So the purpose of this study is to test the combination of Oxaliplatin and Docetaxel in patients with metastatic or locally advanced adenocarcinoma of the pancreas after failure of a palliative first line therapy to get a reasonable second line concept.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Städtische Kliniken Esslingen, Esslingen, Baden Württemberg, Germany
Klinikum Schwäbisch Gmünd, Mutlangen, Baden Württemberg, Germany
Universitätsklinikum Ulm Klinik für Innere Medizin I, Ulm, Baden Württemberg, Germany
Universitätsklinikum Giessen und Marburg GmbH, Marburg, Hessen, Germany
Klinik und Poliklinik für Innere Medizin I / Universitätsklinikum Halle, Halle, , Germany
Name: Thomas Seufferlein, Prof. Dr.
Affiliation: Universitätsklinikum Halle / Klinik für Innere Medizin I
Role: PRINCIPAL_INVESTIGATOR