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Spots Global Cancer Trial Database for Selumetinib and Akt Inhibitor MK2206 or mFOLFOX Therapy Comprising Oxaliplatin and Fluorouracil in Treating Patients With Metastatic Pancreatic Cancer Previously Treated With Chemotherapy

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Selumetinib and Akt Inhibitor MK2206 or mFOLFOX Therapy Comprising Oxaliplatin and Fluorouracil in Treating Patients With Metastatic Pancreatic Cancer Previously Treated With Chemotherapy

Official Title: Randomized Phase II Clinical Trial of AZD6244 Hydrogen Sulfate (NSC-748727) and MK-2206 (NSC-749607) vs mFOLFOX in Patients With Metastatic Pancreatic Cancer After Prior Chemotherapy

Study ID: NCT01658943

Study Description

Brief Summary: This randomized phase II trial studies how well selumetinib and Akt inhibitor MK2206 work compared to modified fluorouracil, leucovorin calcium, and oxaliplatin (mFOLFOX) therapy in treating patients with metastatic pancreatic cancer previously treated with chemotherapy. Selumetinib and Akt inhibitor MK2206 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as oxaliplatin, and fluorouracil, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet know whether selumetinib and Akt inhibitor MK2206 are more effective than oxaliplatin and fluorouracil in treating patients with metastatic pancreatic cancer.

Detailed Description: PRIMARY OBJECTIVES: I. To assess overall survival in patients with metastatic pancreatic cancer treated with the combination of AZD6244 hydrogen sulfate (selumetinib) and MK-2206 (Akt inhibitor MK2206) compared to those treated with mFOLFOX. SECONDARY OBJECTIVES: I. To assess the frequency and severity of toxicity associated with the combination of AZD6244 hydrogen sulfate and MK-2206 compared to those with mFOLFOX in this patient population. TERTIARY OBJECTIVES: I. To assess progression free survival (PFS) in patients with metastatic pancreatic cancer treated with the combination of AZD6244 hydrogen sulfate and MK-2206 compared to those treated with mFOLFOX. II. To assess objective tumor response in the subset of patients with measurable disease (confirmed and unconfirmed complete and partial response) in patients with metastatic pancreatic cancer treated with the combination of AZD6244 hydrogen sulfate and MK-2206 compared to those treated with mFOLFOX. III. To bank tissue and blood for future translational medicine studies. OUTLINE: Patients are randomized to 1 of 2 treatment arms. ARM I: Patients receive oxaliplatin intravenously (IV) over 2 hours on days 1 and 15 and fluorouracil IV over 46-48 hours on days 1-2 and 15-16 (mFOLFOX). ARM II: Patients receive Akt inhibitor MK2206 orally (PO) on days 1, 8, 15, and 22, and selumetinib PO daily on days 1-28. In all arms, courses repeat every 28 days in the absence of disease progression or unacceptable toxicity. After completion of study treatment, patients are followed up every 6 months for up to 3 years.

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

The University of Arizona Cancer Center-Orange Grove Campus, Tucson, Arizona, United States

The University of Arizona Cancer Center-North Campus, Tucson, Arizona, United States

University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

Kaiser Permanente-Anaheim, Anaheim, California, United States

Kaiser Permanente-Deer Valley Medical Center, Antioch, California, United States

Kaiser Permanente-Baldwin Park, Baldwin Park, California, United States

Kaiser Permanente-Bellflower, Bellflower, California, United States

Alta Bates Summit Medical Center-Herrick Campus, Berkeley, California, United States

Mills - Peninsula Hospitals, Burlingame, California, United States

East Bay Radiation Oncology Center, Castro Valley, California, United States

Valley Medical Oncology Consultants-Castro Valley, Castro Valley, California, United States

City of Hope Comprehensive Cancer Center, Duarte, California, United States

Epic Care-Dublin, Dublin, California, United States

Bay Area Breast Surgeons Inc, Emeryville, California, United States

Epic Care Partners in Cancer Care, Emeryville, California, United States

Kaiser Permanente Hospital, Fontana, California, United States

Kaiser Permanente-Fremont, Fremont, California, United States

Valley Medical Oncology Consultants-Fremont, Fremont, California, United States

Kaiser Permanente, Fresno, California, United States

Saint Jude Medical Center, Fullerton, California, United States

Kaiser Permanente - Harbor City, Harbor City, California, United States

Kaiser Permanente-Irvine, Irvine, California, United States

Kaiser Permanente Los Angeles Medical Center, Los Angeles, California, United States

Los Angeles County-USC Medical Center, Los Angeles, California, United States

USC / Norris Comprehensive Cancer Center, Los Angeles, California, United States

Kaiser Permanente-Cadillac, Los Angeles, California, United States

Cedars-Sinai Medical Center, Los Angeles, California, United States

Contra Costa Regional Medical Center, Martinez, California, United States

Fremont - Rideout Cancer Center, Marysville, California, United States

Mercy UC Davis Cancer Center, Merced, California, United States

Kaiser Permanente-Modesto, Modesto, California, United States

El Camino Hospital, Mountain View, California, United States

Sutter Cancer Research Consortium, Novato, California, United States

Highland General Hospital, Oakland, California, United States

Alta Bates Summit Medical Center - Summit Campus, Oakland, California, United States

Bay Area Tumor Institute, Oakland, California, United States

Hematology and Oncology Associates-Oakland, Oakland, California, United States

Tom K Lee Inc, Oakland, California, United States

Kaiser Permanente-Oakland, Oakland, California, United States

Saint Joseph Hospital - Orange, Orange, California, United States

UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange, California, United States

Kaiser Permanente - Panorama City, Panorama City, California, United States

East Bay Medical Oncology Hematology Medical Associates Inc-Pleasant Hill, Pleasant Hill, California, United States

Valley Medical Oncology Consultants, Pleasanton, California, United States

Kaiser Permanente-Redwood City, Redwood City, California, United States

Kaiser Permanente-Richmond, Richmond, California, United States

Kaiser Permanente-Riverside, Riverside, California, United States

Kaiser Permanente-Roseville, Roseville, California, United States

University of California Davis Comprehensive Cancer Center, Sacramento, California, United States

Kaiser Permanente-South Sacramento, Sacramento, California, United States

Kaiser Permanente - Sacramento, Sacramento, California, United States

Saint Helena Hospital, Saint Helena, California, United States

Kaiser Permanente-San Diego Mission, San Diego, California, United States

Kaiser Permanente-San Diego Zion, San Diego, California, United States

Kaiser Permanente-San Francisco, San Francisco, California, United States

California Pacific Medical Center-Pacific Campus, San Francisco, California, United States

Kaiser Permanente-Santa Teresa-San Jose, San Jose, California, United States

Kaiser Permanente San Leandro, San Leandro, California, United States

Kaiser Permanente-San Marcos, San Marcos, California, United States

Doctors Medical Center- JC Robinson Regional Cancer Center, San Pablo, California, United States

Kaiser Permanente-San Rafael, San Rafael, California, United States

Kaiser Permanente Medical Center - Santa Clara, Santa Clara, California, United States

Kaiser Permanente-Santa Rosa, Santa Rosa, California, United States

Sutter Pacific Medical Foundation, Santa Rosa, California, United States

Kaiser Permanente-South San Francisco, South San Francisco, California, United States

Kaiser Permanente-Stockton, Stockton, California, United States

Tahoe Forest Cancer Center, Truckee, California, United States

Kaiser Permanente Medical Center-Vacaville, Vacaville, California, United States

Kaiser Permanente-Vallejo, Vallejo, California, United States

Sutter Solano Medical Center/Cancer Center, Vallejo, California, United States

Kaiser Permanente-Walnut Creek, Walnut Creek, California, United States

Kaiser Permanente, Woodland Hills, California, United States

The Medical Center of Aurora, Aurora, Colorado, United States

Boulder Community Hospital, Boulder, Colorado, United States

Rocky Mountain Cancer Centers-Boulder, Boulder, Colorado, United States

Penrose-Saint Francis Healthcare, Colorado Springs, Colorado, United States

Rocky Mountain Cancer Centers-Penrose, Colorado Springs, Colorado, United States

Kaiser Permanente-Franklin, Denver, Colorado, United States

Porter Adventist Hospital, Denver, Colorado, United States

Colorado Blood Cancer Institute, Denver, Colorado, United States

Exempla Saint Joseph Hospital, Denver, Colorado, United States

Presbyterian - Saint Lukes Medical Center - Health One, Denver, Colorado, United States

Rocky Mountain Cancer Centers-Midtown, Denver, Colorado, United States

Rocky Mountain Cancer Centers-Rose, Denver, Colorado, United States

Rose Medical Center, Denver, Colorado, United States

Colorado Cancer Research Program CCOP, Denver, Colorado, United States

Mercy Medical Center, Durango, Colorado, United States

Comprehensive Cancer Care and Research Institute of Colorado LLC, Englewood, Colorado, United States

Swedish Medical Center, Englewood, Colorado, United States

Poudre Valley Hospital, Fort Collins, Colorado, United States

Front Range Cancer Specialists, Fort Collins, Colorado, United States

Mountain Blue Cancer Care Center, Golden, Colorado, United States

North Colorado Medical Center, Greeley, Colorado, United States

Rocky Mountain Cancer Centers-Greenwood Village, Greenwood Village, Colorado, United States

Kaiser Permanente-Rock Creek, Lafayette, Colorado, United States

Rocky Mountain Cancer Centers-Lakewood, Lakewood, Colorado, United States

Saint Anthony Hospital, Lakewood, Colorado, United States

Littleton Adventist Hospital, Littleton, Colorado, United States

Kaiser Permanente-Lone Tree, Lone Tree, Colorado, United States

Rocky Mountain Cancer Centers-Sky Ridge, Lone Tree, Colorado, United States

Sky Ridge Medical Center, Lone Tree, Colorado, United States

Longmont United Hospital, Longmont, Colorado, United States

Rocky Mountain Cancer Centers-Longmont, Longmont, Colorado, United States

McKee Medical Center, Loveland, Colorado, United States

Parker Adventist Hospital, Parker, Colorado, United States

Rocky Mountain Cancer Centers-Parker, Parker, Colorado, United States

Saint Mary Corwin Medical Center, Pueblo, Colorado, United States

Rocky Mountain Cancer Centers - Pueblo, Pueblo, Colorado, United States

SCL Health Lutheran Medical Center, Wheat Ridge, Colorado, United States

Saint Francis Hospital and Medical Center, Hartford, Connecticut, United States

Middlesex Hospital, Middletown, Connecticut, United States

Stamford Hospital/Bennett Cancer Center, Stamford, Connecticut, United States

Beebe Medical Center, Lewes, Delaware, United States

Christiana Gynecologic Oncology LLC, Newark, Delaware, United States

Delaware Clinical and Laboratory Physicians PA, Newark, Delaware, United States

Helen F Graham Cancer Center, Newark, Delaware, United States

Medical Oncology Hematology Consultants PA, Newark, Delaware, United States

Regional Hematology and Oncology PA, Newark, Delaware, United States

Christiana Care Health System-Christiana Hospital, Newark, Delaware, United States

Beebe Health Campus, Rehoboth Beach, Delaware, United States

Nanticoke Memorial Hospital, Seaford, Delaware, United States

Christiana Care Health System-Wilmington Hospital, Wilmington, Delaware, United States

Baptist Cancer Institute, Jacksonville, Florida, United States

Florida Hospital Orlando, Orlando, Florida, United States

University Cancer and Blood Center LLC, Athens, Georgia, United States

Georgia Regents University Medical Center, Augusta, Georgia, United States

Dekalb Medical Center, Decatur, Georgia, United States

Northeast Georgia Medical Center, Gainesville, Georgia, United States

Medical Center of Central Georgia, Macon, Georgia, United States

Lewis Cancer and Research Pavilion at Saint Joseph's/Candler, Savannah, Georgia, United States

South Georgia Medical Center, Valdosta, Georgia, United States

Oncare Hawaii Inc-Pali Momi, Aiea, Hawaii, United States

Pali Momi Medical Center, Aiea, Hawaii, United States

Oncare Hawaii Inc-POB II, Honolulu, Hawaii, United States

Queen's Medical Center, Honolulu, Hawaii, United States

Straub Clinic and Hospital, Honolulu, Hawaii, United States

University of Hawaii Cancer Center, Honolulu, Hawaii, United States

OnCare Hawaii-Liliha, Honolulu, Hawaii, United States

Oncare Hawaii Inc-Kuakini, Honolulu, Hawaii, United States

Kaiser Permanente Moanalua Medical Center, Honolulu, Hawaii, United States

Castle Medical Center, Kailua, Hawaii, United States

Wilcox Memorial Hospital and Kauai Medical Clinic, Lihue, Hawaii, United States

Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho, United States

Idaho Urologic Institute-Meridian, Meridian, Idaho, United States

Kootenai Cancer Center, Post Falls, Idaho, United States

Rush - Copley Medical Center, Aurora, Illinois, United States

Memorial Hospital of Carbondale, Carbondale, Illinois, United States

Centralia Oncology Clinic, Centralia, Illinois, United States

Northwestern University, Chicago, Illinois, United States

Rush University Medical Center, Chicago, Illinois, United States

University of Illinois, Chicago, Illinois, United States

University of Chicago Comprehensive Cancer Center, Chicago, Illinois, United States

Weiss Memorial Hospital, Chicago, Illinois, United States

Cancer Care Center of Decatur, Decatur, Illinois, United States

Central Illinois CCOP, Decatur, Illinois, United States

Decatur Memorial Hospital, Decatur, Illinois, United States

Crossroads Cancer Center, Effingham, Illinois, United States

Advocate Sherman Hospital, Elgin, Illinois, United States

Ingalls Memorial Hospital, Harvey, Illinois, United States

Hematology Oncology Associates of Illinois-Highland Park, Highland Park, Illinois, United States

Joliet Oncology-Hematology Associates Limited, Joliet, Illinois, United States

Presence Saint Mary's Hospital, Kankakee, Illinois, United States

NorthShore Hematology Oncology-Libertyville, Libertyville, Illinois, United States

Loyola University Medical Center, Maywood, Illinois, United States

Good Samaritan Regional Health Center, Mount Vernon, Illinois, United States

Illinois Cancer Specialists-Niles, Niles, Illinois, United States

West Suburban Medical Center, River Forest, Illinois, United States

Hematology Oncology Associates of Illinois - Skokie, Skokie, Illinois, United States

Memorial Medical Center, Springfield, Illinois, United States

Carle Cancer Center, Urbana, Illinois, United States

Franciscan St. Francis Health-Beech Grove, Beech Grove, Indiana, United States

Elkhart Clinic, Elkhart, Indiana, United States

Michiana Hematology Oncology PC-Elkhart, Elkhart, Indiana, United States

Elkhart General Hospital, Elkhart, Indiana, United States

Fort Wayne Medical Oncology and Hematology Inc-Parkview, Fort Wayne, Indiana, United States

Indiana University/Melvin and Bren Simon Cancer Center, Indianapolis, Indiana, United States

IU Health Central Indiana Cancer Centers-East, Indianapolis, Indiana, United States

Franciscan Saint Francis Health-Indianapolis, Indianapolis, Indiana, United States

Community Howard Regional Health, Kokomo, Indiana, United States

IU Health La Porte Hospital, La Porte, Indiana, United States

Franciscan Saint Anthony Health-Michigan City, Michigan City, Indiana, United States

Cancer Care Partners LLC, Mishawaka, Indiana, United States

Michiana Hematology Oncology PC-Mishawaka, Mishawaka, Indiana, United States

Saint Joseph Regional Medical Center-Mishawaka, Mishawaka, Indiana, United States

Michiana Hematology Oncology PC-Plymouth, Plymouth, Indiana, United States

Reid Hospital and Health Care Services, Richmond, Indiana, United States

Memorial Hospital of South Bend, South Bend, Indiana, United States

Michiana Hematology Oncology PC-South Bend, South Bend, Indiana, United States

South Bend Clinic, South Bend, Indiana, United States

Northern Indiana Cancer Research Consortium CCOP, South Bend, Indiana, United States

Michiana Hematology Oncology PC-Westville, Westville, Indiana, United States

Hematology Oncology Associates-Quad Cities, Bettendorf, Iowa, United States

Genesis Medical Center - East Campus, Davenport, Iowa, United States

Siouxland Regional Cancer Center, Sioux City, Iowa, United States

Mercy Medical Center-Sioux City, Sioux City, Iowa, United States

Saint Luke's Regional Medical Center, Sioux City, Iowa, United States

Cancer Center of Kansas - Chanute, Chanute, Kansas, United States

Cancer Center of Kansas - Dodge City, Dodge City, Kansas, United States

Cancer Center of Kansas - El Dorado, El Dorado, Kansas, United States

Cancer Center of Kansas - Fort Scott, Fort Scott, Kansas, United States

Cancer Center of Kansas-Independence, Independence, Kansas, United States

Providence Medical Center, Kansas City, Kansas, United States

Cancer Center of Kansas-Kingman, Kingman, Kansas, United States

Lawrence Memorial Hospital, Lawrence, Kansas, United States

Cancer Center of Kansas-Liberal, Liberal, Kansas, United States

Cancer Center of Kansas-Manhattan, Manhattan, Kansas, United States

Cancer Center of Kansas - McPherson, McPherson, Kansas, United States

Cancer Center of Kansas - Newton, Newton, Kansas, United States

Menorah Medical Center, Overland Park, Kansas, United States

Saint Luke's South Hospital, Overland Park, Kansas, United States

Cancer Center of Kansas - Parsons, Parsons, Kansas, United States

Kansas City CCOP, Prairie Village, Kansas, United States

Cancer Center of Kansas - Pratt, Pratt, Kansas, United States

Cancer Center of Kansas - Salina, Salina, Kansas, United States

Cancer Center of Kansas - Wellington, Wellington, Kansas, United States

Associates In Womens Health, Wichita, Kansas, United States

Cancer Center of Kansas-Wichita Medical Arts Tower, Wichita, Kansas, United States

Cancer Center of Kansas - Main Office, Wichita, Kansas, United States

Via Christi Regional Medical Center, Wichita, Kansas, United States

Wichita CCOP, Wichita, Kansas, United States

Cancer Center of Kansas - Winfield, Winfield, Kansas, United States

Oncology Hematology Care Inc-Crestview, Crestview Hills, Kentucky, United States

Hematology/Oncology Clinic LLP, Baton Rouge, Louisiana, United States

Mary Bird Perkins Cancer Center, Baton Rouge, Louisiana, United States

Ochsner Health Center-Summa, Baton Rouge, Louisiana, United States

Cancer Center of Acadiana, Lafayette, Louisiana, United States

DeSoto Regional Health System, Mansfield, Louisiana, United States

University Health-Conway, Monroe, Louisiana, United States

Louisiana State University Health Science Center, New Orleans, Louisiana, United States

Tulane University Health Sciences Center, New Orleans, Louisiana, United States

Ochsner Baptist Medical Center, New Orleans, Louisiana, United States

Ochsner Medical Center Jefferson, New Orleans, Louisiana, United States

Louisiana State University Health Sciences Center Shreveport, Shreveport, Louisiana, United States

Highland Clinic, Shreveport, Louisiana, United States

Harold Alfond Center for Cancer Care, Augusta, Maine, United States

Eastern Maine Medical Center, Bangor, Maine, United States

Union Hospital of Cecil County, Elkton MD, Maryland, United States

Bixby Medical Center, Adrian, Michigan, United States

Hickman Cancer Center, Adrian, Michigan, United States

Saint Joseph Mercy Hospital, Ann Arbor, Michigan, United States

Michigan Cancer Research Consortium CCOP, Ann Arbor, Michigan, United States

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States

Bronson Battle Creek, Battle Creek, Michigan, United States

Spectrum Health Big Rapids Hospital, Big Rapids, Michigan, United States

Huron Valley-Sinai Hospital, Commerce, Michigan, United States

Oakwood Hospital and Medical Center, Dearborn, Michigan, United States

Wayne State University/Karmanos Cancer Institute, Detroit, Michigan, United States

Saint John Hospital and Medical Center, Detroit, Michigan, United States

Hurley Medical Center, Flint, Michigan, United States

Genesys Hurley Cancer Institute, Flint, Michigan, United States

Genesys Regional Medical Center, Grand Blanc, Michigan, United States

Grand Rapids Clinical Oncology Program, Grand Rapids, Michigan, United States

Mercy Health Saint Mary's, Grand Rapids, Michigan, United States

Spectrum Health at Butterworth Campus, Grand Rapids, Michigan, United States

Allegiance Health, Jackson, Michigan, United States

Borgess Medical Center, Kalamazoo, Michigan, United States

Bronson Methodist Hospital, Kalamazoo, Michigan, United States

West Michigan Cancer Center, Kalamazoo, Michigan, United States

Sparrow Hospital, Lansing, Michigan, United States

Saint Mary Mercy Hospital, Livonia, Michigan, United States

Mercy Memorial Hospital, Monroe, Michigan, United States

Toledo Clinic Cancer Centers-Monroe, Monroe, Michigan, United States

Mercy Health Mercy Campus, Muskegon, Michigan, United States

Saint Joseph Mercy Oakland, Pontiac, Michigan, United States

Saint Joseph Mercy Port Huron, Port Huron, Michigan, United States

Spectrum Health Reed City Hospital, Reed City, Michigan, United States

Saint Mary's of Michigan, Saginaw, Michigan, United States

Marie Yeager Cancer Center, Saint Joseph, Michigan, United States

Providence Hospital-Southfield Cancer Center, Southfield, Michigan, United States

Lakeland Hospital, St. Joseph, Michigan, United States

Munson Medical Center, Traverse City, Michigan, United States

Saint John Macomb-Oakland Hospital, Warren, Michigan, United States

Sanford Clinic North-Bemidgi, Bemidji, Minnesota, United States

Fairview Ridges Hospital, Burnsville, Minnesota, United States

Mercy Hospital, Coon Rapids, Minnesota, United States

Fairview-Southdale Hospital, Edina, Minnesota, United States

Unity Hospital, Fridley, Minnesota, United States

Hutchinson Area Health Care, Hutchinson, Minnesota, United States

Minnesota Oncology Hematology PA-Maplewood, Maplewood, Minnesota, United States

Saint John's Hospital - Healtheast, Maplewood, Minnesota, United States

Abbott-Northwestern Hospital, Minneapolis, Minnesota, United States

Hennepin County Medical Center, Minneapolis, Minnesota, United States

New Ulm Medical Center, New Ulm, Minnesota, United States

North Memorial Medical Health Center, Robbinsdale, Minnesota, United States

Coborn Cancer Center at Saint Cloud Hospital, Saint Cloud, Minnesota, United States

Saint Cloud Hospital, Saint Cloud, Minnesota, United States

Metro Minnesota Community Oncology Research Consortium, Saint Louis Park, Minnesota, United States

Park Nicollet Clinic - Saint Louis Park, Saint Louis Park, Minnesota, United States

Regions Hospital, Saint Paul, Minnesota, United States

United Hospital, Saint Paul, Minnesota, United States

Saint Francis Regional Medical Center, Shakopee, Minnesota, United States

Lakeview Hospital, Stillwater, Minnesota, United States

Ridgeview Medical Center, Waconia, Minnesota, United States

Rice Memorial Hospital, Willmar, Minnesota, United States

Minnesota Oncology and Hematology PA-Woodbury, Woodbury, Minnesota, United States

University of Mississippi Medical Center, Jackson, Mississippi, United States

Saint Francis Medical Center, Cape Girardeau, Missouri, United States

Southeast Cancer Center, Cape Girardeau, Missouri, United States

University of Missouri - Ellis Fischel, Columbia, Missouri, United States

Centerpoint Medical Center LLC, Independence, Missouri, United States

Capital Region Medical Center-Goldschmidt Cancer Center, Jefferson City, Missouri, United States

Saint Luke's Hospital of Kansas City, Kansas City, Missouri, United States

North Kansas City Hospital, Kansas City, Missouri, United States

Heartland Hematology and Oncology Associates Incorporated, Kansas City, Missouri, United States

Kansas City Veterans Affairs Medical Center, Kansas City, Missouri, United States

Research Medical Center, Kansas City, Missouri, United States

Saint Luke's East - Lee's Summit, Lee's Summit, Missouri, United States

Liberty Radiation Oncology Center, Liberty, Missouri, United States

Phelps County Regional Medical Center, Rolla, Missouri, United States

Saint John's Clinic-Rolla-Cancer and Hematology, Rolla, Missouri, United States

Heartland Regional Medical Center, Saint Joseph, Missouri, United States

Saint Joseph Oncology Inc, Saint Joseph, Missouri, United States

Saint Louis Cancer and Breast Institute-South City, Saint Louis, Missouri, United States

Washington University School of Medicine, Saint Louis, Missouri, United States

Missouri Baptist Medical Center, Saint Louis, Missouri, United States

Mercy Hospital Saint Louis, Saint Louis, Missouri, United States

Cancer Research for the Ozarks NCORP, Springfield, Missouri, United States

Mercy Hospital Springfield, Springfield, Missouri, United States

CoxHealth South Hospital, Springfield, Missouri, United States

Montana Cancer Consortium NCORP, Billings, Montana, United States

Saint Vincent Healthcare, Billings, Montana, United States

Frontier Cancer Center and Blood Institute-Billings, Billings, Montana, United States

Billings Clinic Cancer Center, Billings, Montana, United States

Bozeman Deaconess Hospital, Bozeman, Montana, United States

Saint James Community Hospital and Cancer Treatment Center, Butte, Montana, United States

Benefis Healthcare- Sletten Cancer Institute, Great Falls, Montana, United States

Big Sky Oncology, Great Falls, Montana, United States

Saint Peter's Community Hospital, Helena, Montana, United States

Kalispell Medical Oncology, Kalispell, Montana, United States

Kalispell Regional Medical Center, Kalispell, Montana, United States

Montana Cancer Specialists, Missoula, Montana, United States

Saint Patrick Hospital - Community Hospital, Missoula, Montana, United States

CHI Health Good Samaritan, Kearney, Nebraska, United States

Nebraska Cancer Research Center, Lincoln, Nebraska, United States

Missouri Valley Cancer Consortium, Omaha, Nebraska, United States

Alegent Health Immanuel Medical Center, Omaha, Nebraska, United States

Alegent Health Bergan Mercy Medical Center, Omaha, Nebraska, United States

Alegent Health Lakeside Hospital, Omaha, Nebraska, United States

Creighton University Medical Center, Omaha, Nebraska, United States

University Medical Center of Southern Nevada, Las Vegas, Nevada, United States

Nevada Cancer Research Foundation CCOP, Las Vegas, Nevada, United States

Cooper Hospital University Medical Center, Camden, New Jersey, United States

Veterans Adminstration New Jersey Health Care System, East Orange, New Jersey, United States

AtlantiCare Surgery Center, Egg Harbor Township, New Jersey, United States

Englewood Hospital and Medical Center, Englewood, New Jersey, United States

UMDNJ - New Jersey Medical School, Newark, New Jersey, United States

Albert Einstein College of Medicine, Bronx, New York, United States

Montefiore Medical Center - Moses Campus, Bronx, New York, United States

Kings County Hospital, Brooklyn, New York, United States

State University of New York Downstate Medical Center, Brooklyn, New York, United States

Mary Imogene Bassett Hospital, Cooperstown, New York, United States

Glens Falls Hospital, Glens Falls, New York, United States

Orange Regional Medical Center, Middletown, New York, United States

Winthrop University Hospital, Mineola, New York, United States

Columbia University Medical Center, New York, New York, United States

University of Rochester, Rochester, New York, United States

Staten Island University Hospital, Staten Island, New York, United States

Randolph Hospital, Asheboro, North Carolina, United States

Wayne Memorial Hospital, Goldsboro, North Carolina, United States

Cone Health Cancer Center, Greensboro, North Carolina, United States

Kinston Medical Specialists PA, Kinston, North Carolina, United States

FirstHealth of the Carolinas-Moore Regional Hosiptal, Pinehurst, North Carolina, United States

Annie Penn Memorial Hospital, Reidsville, North Carolina, United States

Iredell Memorial Hospital, Statesville, North Carolina, United States

Southeast Cancer Control Consortium CCOP, Winston-Salem, North Carolina, United States

Mid Dakota Clinic, Bismarck, North Dakota, United States

Saint Alexius Medical Center, Bismarck, North Dakota, United States

Sanford Bismarck Medical Center, Bismarck, North Dakota, United States

Roger Maris Cancer Center, Fargo, North Dakota, United States

Sanford Clinic North-Fargo, Fargo, North Dakota, United States

Sanford Medical Center-Fargo, Fargo, North Dakota, United States

Summa Akron City Hospital/Cooper Cancer Center, Akron, Ohio, United States

Akron General Medical Center, Akron, Ohio, United States

Summa Barberton Hospital, Barberton, Ohio, United States

Cleveland Clinic Cancer Center Beachwood, Beachwood, Ohio, United States

Strecker Cancer Center-Belpre, Belpre, Ohio, United States

Toledo Clinic Cancer Centers-Bowling Green, Bowling Green, Ohio, United States

Adena Regional Medical Center, Chillicothe, Ohio, United States

Oncology Hematology Care Inc-Eden Park, Cincinnati, Ohio, United States

Oncology Hematology Care Inc-Mercy West, Cincinnati, Ohio, United States

Good Samaritan Hospital - Cincinnati, Cincinnati, Ohio, United States

Oncology Hematology Care Inc - Anderson, Cincinnati, Ohio, United States

Oncology Hematology Care Inc - Kenwood, Cincinnati, Ohio, United States

Bethesda North Hospital, Cincinnati, Ohio, United States

Oncology Hematology Care Inc-Blue Ash, Cincinnati, Ohio, United States

Case Western Reserve University, Cleveland, Ohio, United States

MetroHealth Medical Center, Cleveland, Ohio, United States

Cleveland Clinic Cancer Center/Fairview Hospital, Cleveland, Ohio, United States

Cleveland Clinic Foundation, Cleveland, Ohio, United States

Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States

Columbus Oncology and Hematology Associates Inc, Columbus, Ohio, United States

Riverside Methodist Hospital, Columbus, Ohio, United States

Columbus CCOP, Columbus, Ohio, United States

Grant Medical Center, Columbus, Ohio, United States

The Mark H Zangmeister Center, Columbus, Ohio, United States

Mount Carmel Health Center West, Columbus, Ohio, United States

Doctors Hospital, Columbus, Ohio, United States

Grandview Hospital, Dayton, Ohio, United States

Good Samaritan Hospital - Dayton, Dayton, Ohio, United States

Miami Valley Hospital, Dayton, Ohio, United States

Samaritan North Health Center, Dayton, Ohio, United States

Dayton CCOP, Dayton, Ohio, United States

Delaware Health Center-Grady Cancer Center, Delaware, Ohio, United States

Delaware Radiation Oncology, Delaware, Ohio, United States

Grady Memorial Hospital, Delaware, Ohio, United States

Hematology Oncology Center Incorporated, Elyria, Ohio, United States

Mercy Cancer Center-Elyria, Elyria, Ohio, United States

Oncology Hematology Care Inc-Healthplex, Fairfield, Ohio, United States

Blanchard Valley Hospital, Findlay, Ohio, United States

Atrium Medical Center-Middletown Regional Hospital, Franklin, Ohio, United States

Wayne Hospital, Greenville, Ohio, United States

Kettering Medical Center, Kettering, Ohio, United States

Fairfield Medical Center, Lancaster, Ohio, United States

Lancaster Radiation Oncology, Lancaster, Ohio, United States

Saint Rita's Medical Center, Lima, Ohio, United States

Lima Memorial Hospital, Lima, Ohio, United States

Marietta Memorial Hospital, Marietta, Ohio, United States

Toledo Clinic Cancer Centers-Maumee, Maumee, Ohio, United States

Toledo Radiation Oncology at Northwest Ohio Onocolgy Center, Maumee, Ohio, United States

Hillcrest Hospital Cancer Center, Mayfield Heights, Ohio, United States

Knox Community Hospital, Mount Vernon, Ohio, United States

Licking Memorial Hospital, Newark, Ohio, United States

Newark Radiation Oncology, Newark, Ohio, United States

Saint Charles Hospital, Oregon, Ohio, United States

Toledo Clinic Cancer Centers-Oregon, Oregon, Ohio, United States

Southern Ohio Medical Center, Portsmouth, Ohio, United States

North Coast Cancer Care, Sandusky, Ohio, United States

Springfield Regional Medical Center, Springfield, Ohio, United States

Cleveland Clinic Cancer Center Strongsville, Strongsville, Ohio, United States

Flower Hospital, Sylvania, Ohio, United States

Mercy Hospital of Tiffin, Tiffin, Ohio, United States

The Toledo Hospital/Toledo Children's Hospital, Toledo, Ohio, United States

Saint Vincent Mercy Medical Center, Toledo, Ohio, United States

University of Toledo, Toledo, Ohio, United States

Toledo Community Hospital Oncology Program CCOP, Toledo, Ohio, United States

Mercy Saint Anne Hospital, Toledo, Ohio, United States

Toledo Clinic Cancer Centers-Toledo, Toledo, Ohio, United States

Upper Valley Medical Center, Troy, Ohio, United States

Fulton County Health Center, Wauseon, Ohio, United States

Saint Ann's Hospital, Westerville, Ohio, United States

Cleveland Clinic Wooster Specialty Center, Wooster, Ohio, United States

Greene Memorial Hospital, Xenia, Ohio, United States

Genesis HealthCare System, Zanesville, Ohio, United States

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States

Oklahoma Oncology Inc, Tulsa, Oklahoma, United States

Natalie Warren Bryant Cancer Center at Saint Francis, Tulsa, Oklahoma, United States

Warren Cancer Research Foundation, Tulsa, Oklahoma, United States

Tulsa Cancer Institute, Tulsa, Oklahoma, United States

Legacy Mount Hood Medical Center, Gresham, Oregon, United States

Legacy Good Samaritan Hospital and Medical Center, Portland, Oregon, United States

Legacy Emanuel Hospital and Health Center, Portland, Oregon, United States

Legacy Meridian Park Hospital, Tualatin, Oregon, United States

Abington Memorial Hospital, Abington, Pennsylvania, United States

Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania, United States

Lehigh Valley Hospital - Muhlenberg, Bethlehem, Pennsylvania, United States

Bryn Mawr Hospital, Bryn Mawr, Pennsylvania, United States

Geisinger Medical Center, Danville, Pennsylvania, United States

Geisinger Medical Center-Cancer Center Hazleton, Hazleton, Pennsylvania, United States

Lancaster General Hospital, Lancaster, Pennsylvania, United States

Geisinger Medical Oncology-Lewisburg, Lewisburg, Pennsylvania, United States

Paoli Memorial Hospital, Paoli, Pennsylvania, United States

University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania, United States

Geisinger Medical Oncology-Pottsville, Pottsville, Pennsylvania, United States

Guthrie Medical Group PC-Robert Packer Hospital, Sayre, Pennsylvania, United States

Geisinger Medical Group, State College, Pennsylvania, United States

Reading Hospital, West Reading, Pennsylvania, United States

Geisinger Wyoming Valley/Henry Cancer Center, Wilkes-Barre, Pennsylvania, United States

Lankenau Medical Center, Wynnewood, Pennsylvania, United States

Mainline Health CCOP, Wynnewood, Pennsylvania, United States

Sanford Cancer Center-Oncology Clinic, Sioux Falls, South Dakota, United States

Avera Cancer Institute, Sioux Falls, South Dakota, United States

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota, United States

Erlanger Medical Center, Chattanooga, Tennessee, United States

Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee, United States

The Don and Sybil Harrington Cancer Center, Amarillo, Texas, United States

Texas Tech University Health Sciences Center, Lubbock, Texas, United States

Huntsman Cancer Institute/University of Utah, Salt Lake City, Utah, United States

Danville Hematology Oncology, Danville, Virginia, United States

Danville Regional Medical Center, Danville, Virginia, United States

Fredericksburg Oncology Inc, Fredericksburg, Virginia, United States

Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia, United States

Cancer Care Center at Island Hospital, Anacortes, Washington, United States

PeaceHealth Saint Joseph Medical Center, Bellingham, Washington, United States

Harrison HealthPartners Hematology and Oncology-Bremerton, Bremerton, Washington, United States

Highline Medical Center-Main Campus, Burien, Washington, United States

Swedish Medical Center-Edmonds, Edmonds, Washington, United States

Swedish Cancer Institute-Issaquah, Issaquah, Washington, United States

Kadlec Clinic Hematology and Oncology, Kennewick, Washington, United States

Seattle Cancer Care Alliance at EvergreenHealth, Kirkland, Washington, United States

Skagit Valley Hospital, Mount Vernon, Washington, United States

Harrison HealthPartners Hematology and Oncology-Poulsbo, Poulsbo, Washington, United States

Harborview Medical Center, Seattle, Washington, United States

Minor and James Medical PLLC, Seattle, Washington, United States

Swedish Medical Center-Ballard Campus, Seattle, Washington, United States

Fred Hutchinson Cancer Research Center, Seattle, Washington, United States

Group Health Cooperative of Puget Sound Oncology Consortium, Seattle, Washington, United States

Group Health Cooperative-Seattle, Seattle, Washington, United States

Swedish Medical Center-First Hill, Seattle, Washington, United States

University of Washington Medical Center, Seattle, Washington, United States

United General Hospital, Sedro-Woolley, Washington, United States

Cancer Care Northwest - Spokane South, Spokane, Washington, United States

Evergreen Hematology and Oncology PS, Spokane, Washington, United States

Rockwood Clinic, Spokane, Washington, United States

Legacy Salmon Creek Hospital, Vancouver, Washington, United States

Wenatchee Valley Hospital and Clinics, Wenatchee, Washington, United States

West Virginia University Charleston, Charleston, West Virginia, United States

West Virginia University Healthcare, Morgantown, West Virginia, United States

Langlade Hospital and Cancer Center, Antigo, Wisconsin, United States

Marshfield Clinic-Chippewa Center, Chippewa Falls, Wisconsin, United States

Marshfield Clinic Cancer Center at Sacred Heart, Eau Claire, Wisconsin, United States

Sacred Heart Hospital, Eau Claire, Wisconsin, United States

Gundersen Lutheran Medical Center, La Crosse, Wisconsin, United States

Marshfield Clinic - Ladysmith Center, Ladysmith, Wisconsin, United States

Dean Hematology and Oncology Clinic, Madison, Wisconsin, United States

Marshfield Clinic, Marshfield, Wisconsin, United States

Saint Joseph's Hospital, Marshfield, Wisconsin, United States

Marshfield Clinic-Minocqua Center, Minocqua, Wisconsin, United States

D N Greenwald Center, Mukwonago, Wisconsin, United States

Cancer Center of Western Wisconsin, New Richmond, Wisconsin, United States

Oconomowoc Memorial Hospital-ProHealth Care Inc, Oconomowoc, Wisconsin, United States

Marshfield Clinic at James Beck Cancer Center, Rhinelander, Wisconsin, United States

Saint Mary's Hospital, Rhinelander, Wisconsin, United States

Marshfield Clinic-Rice Lake Center, Rice Lake, Wisconsin, United States

Marshfield Clinic Cancer Care at Saint Michael's Hospital, Stevens Point, Wisconsin, United States

Saint Michael's Hospital, Stevens Point, Wisconsin, United States

Waukesha Memorial Hospital, Waukesha, Wisconsin, United States

Aspirus Regional Cancer Center, Wausau, Wisconsin, United States

Marshfield Clinic-Wausau Center, Wausau, Wisconsin, United States

Diagnostic and Treatment Center, Weston, Wisconsin, United States

Marshfield Clinic - Weston Center, Weston, Wisconsin, United States

Saint Clare's Hospital, Weston, Wisconsin, United States

Marshfield Clinic - Wisconsin Rapids Center, Wisconsin Rapids, Wisconsin, United States

Rocky Mountain Oncology, Casper, Wyoming, United States

Welch Cancer Center, Sheridan, Wyoming, United States

Contact Details

Name: Vincent Chung

Affiliation: SWOG Cancer Research Network

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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