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Spots Global Cancer Trial Database for Study Evaluating Efficacy and Safety of FFX Versus Combination of CPI-613 With mFFX in Patients With Metastatic Adenocarcinoma of the Pancreas

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Trial Identification

Brief Title: Study Evaluating Efficacy and Safety of FFX Versus Combination of CPI-613 With mFFX in Patients With Metastatic Adenocarcinoma of the Pancreas

Official Title: A Phase III Multicenter Open-label Randomized Trial to Evaluate Efficacy and Safety of Folfirinox (FFX) Versus Combination of CPI-613 With Modified Folfirinox (mFFX) in Patients With Metastatic Adenocarcinoma of the Pancreas

Study ID: NCT03504423

Study Description

Brief Summary: A prospective, multicenter, open label, randomized phase III study to evaluate efficacy and safety of FFX versus CPI-613 + mFFX in patients with metastatic adenocarcinoma of the pancreas with age range of 18 to 75 years

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Banner MD Anderson Cancer Center, Gilbert, Arizona, United States

The University of Arizona Cancer Center, Tucson, Arizona, United States

City of Hope, Duarte, California, United States

USC Norris Comprehensive Cancer Center, Los Angeles, California, United States

UCLA Medical Center, Los Angeles, California, United States

Pacific Hematology Oncology Associates, San Francisco, California, United States

Smilow Cancer Hospital at Yale-New Haven, New Haven, Connecticut, United States

Georgetown University Medical Center, Washington, District of Columbia, United States

Mayo Clinic Hospital, Jacksonville, Florida, United States

Mount Sinai Medical Center, Miami Beach, Florida, United States

Northwestern Memorial Hospital - Arkes Family Pavilion, Chicago, Illinois, United States

University of Chicago, Harvey, Illinois, United States

The University of Kansas Cancer Center - Clinical Research Center - Fairway Office Park, Fairway, Kansas, United States

University of Massachusetts Memorial Medical Center, Worcester, Massachusetts, United States

University of Micihgan, Ann Arbor, Michigan, United States

Karmanos cancer Center, Detroit, Michigan, United States

Mayo Clinic Cancer Center (MCCC), Rochester, Minnesota, United States

Washington University, Saint Louis, Missouri, United States

Comprehensive Cancer centers of Nevada, Las Vegas, Nevada, United States

Englewood Hospital and Medical Center, Englewood, New Jersey, United States

Atlantic Health System, Morristown, New Jersey, United States

University of New Mexico Cancer Center, Albuquerque, New Mexico, United States

Roswell Park Cancer Institute, Buffalo, New York, United States

New York University Langone Medical Center, New York, New York, United States

Stony Brook University Hospital, Stony Brook, New York, United States

UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, United States

Levine cancer Institute, Charlotte, North Carolina, United States

Wake Forest Baptist Health, Winston-Salem, North Carolina, United States

University of Cincinnati Cancer Institute, Cincinnati, Ohio, United States

Cleveland Clinic - Taussig Cancer Center, Cleveland, Ohio, United States

University Hospitals - Seidman Cancer Center, Cleveland, Ohio, United States

Oregon Health and Science University, Portland, Oregon, United States

University of Pittsburgh-Hillman cancer ceter, Pittsburgh, Pennsylvania, United States

Vanderbilt University Medical Center-Vanderbilt-Ingram Cancer Center-Henry-Joyce Cancer Clinic, Nashville, Tennessee, United States

The University of Texas MD Anderson Cancer Center, Houston, Texas, United States

Huntsman cancer Institute, Salt Lake City, Utah, United States

University of Virginia Cancer Center - Emily Couric Clinical Cancer Center, Charlottesville, Virginia, United States

VCU Massey Cancer Center, Richmond, Virginia, United States

Blue Ridge Cancer Care, Roanoke, Virginia, United States

Seattle Cancer Care Alliance, Seattle, Washington, United States

Hôpital Erasme, Bruxelles, Brussel, Belgium

UZ Leuven, Leuven, VBR, Belgium

CHRU Brest - Hôpital Morvan, Brest, , France

Hôpital Beaujon, Clichy, , France

Centre Hospitalier Départemental Vendée - Hôpital de la Roche-sur-Yon, La Roche-sur-Yon, , France

L'ICM, Institut régional du Cancer de Montpellier, Montpellier, , France

CHU de Nantes - Hôpital Nord Laennec, Nantes Cedex 1, , France

CHU Hopitaux de Bordeaux - Hôpital Saint-André, Pessac, , France

CHU de Poitiers, Poitiers, , France

Centre Eugène Marquis, Rennes, , France

Institut de Cancérologie de Lorraine, Vandœuvre-lès-Nancy, , France

Gustave Roussy Cancer Campus Grand Paris (Institut de Cancerologie Gustave-Roussy), Villejuif, , France

SLK-Kliniken Heilbronn GmbH, Heilbronn, BW, Germany

Universitätsklinikum Knappschaftskrankenhaus Bochum GmbH, Bochum, , Germany

Universitaetsklinikum Tuebingen, Tuebingen, , Germany

Hillel Yaffe Medical Center, Hadera, Haifa, Israel

Rambam Medical Center, Haifa, , Israel

Shaare Zedek Medical Center, Jerusalem, , Israel

Sanz Medical Center - Laniado Hospital, Netanya, , Israel

The Chaim Sheba Medical Center - Sheba Cancer Research Center (SCRC), Ramat Gan, , Israel

Tel Aviv Sourasky Medical Center, Tel Aviv, , Israel

Assaf-Harofeh Medical Center, Zerifin, , Israel

The Catholic University of Korea - Seoul St. Mary's Hospital (Kangnam St. Mary's Hospital), Seocho, Seoul, Korea, Republic of

Seoul National University Hospital, Busan, , Korea, Republic of

Kyungpook National University Chilgok Hospital, Daegu, , Korea, Republic of

Gachon University Gil Hospital, Incheon, , Korea, Republic of

Inha University Hospital, Incheon, , Korea, Republic of

Seoul National University Bundang Hospital, Seongnam-si, , Korea, Republic of

Seoul National University Hospital, Seoul, , Korea, Republic of

Korea University Anam Hospital, Seoul, , Korea, Republic of

Severance Hospital - Yonsei Cancer Center, Seoul, , Korea, Republic of

Samsung Medical Center, Seoul, , Korea, Republic of

National Cancer Center, Seoul, , Korea, Republic of

Ajou University Hospital, Suwon, , Korea, Republic of

Contact Details

Name: Philip A Philip, MD, PhD, FRCP

Affiliation: Karmanos Cancer Institute at Wayne State University

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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