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Brief Title: Study With M2ES and Gemcitabine for Patients With Advanced Pancreatic Cancer
Official Title: Phase I Study of M2ES Combined Gemcitabine in Patients With Advanced Pancreatic Cancer
Study ID: NCT01218880
Brief Summary: Phase I trail will be conducted to evaluate the safety of M2ES in combination with gemcitabine in locally advanced or metastatic pancreatic cancer.
Detailed Description: Phase I trail will be conducted to determine the MTD and safety of M2ES(administered intravenous infusion on Days 1,8,15,21of a 28-day cycle) in combination with gemcitabine (1000 m/m2). Gemcitabine will be administered as an intravenous infusion on Days 1, 8, and 15 of each 28-day cycle,at the same time determine the safety and efficiency of this combined regime.
Minimum Age: 18 Years
Eligible Ages: ADULT
Sex: ALL
Healthy Volunteers: No
Shanghai Changhai Hospital, Shanghai, Shanghai, China
Name: Zhaosheng Li, MD
Affiliation: Shanghai Changhai Hosptial
Role: PRINCIPAL_INVESTIGATOR