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Brief Title: Gemcitabine and Capecitabine to Treat Patients With Advanced Pancreatic and Biliary Cancers
Official Title: A Phase I Study, With Expanded Cohort, of Biweekly Fixed-dose Rate Gemcitabine Plus Capecitabine in Patients With Advanced Pancreatic and Biliary Carcinomas
Study ID: NCT00626158
Brief Summary: The purpose of this study is to find out what effects gemcitabine plus capecitabine has on patients with pancreatic or biliary cancer, and to determine the optimal dose that can be given safely of these two drugs together (called the maximum tolerated dose). Gemcitabine and capecitabine are two chemotherapy drugs used to treat pancreatic and biliary cancer. These two drugs used together are considered an acceptable standard of care for pancreatic and biliary cancers. However, in this study the dose and dosing schedule will be changed, in the hopes that the drugs will have more effect with fewer side effects than when given in the standard way.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California, United States
Huntsman Cancer Center, University of Utah, Salt Lake City, Utah, United States
Name: Andrew Ko, MD
Affiliation: University of California, San Francisco
Role: PRINCIPAL_INVESTIGATOR