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Brief Title: Phase III of Gemcitabine Vs TS-1 Vs Gemcitabine Plus TS-1 in Pancreatic Cancer
Official Title: Randomized Phase III Study of Gemcitabine Versus TS-1 Versus Gemcitabine Plus TS-1 in Unresectable Advanced Pancreatic Cancer (With Local Progression or Metastasis)
Study ID: NCT00498225
Brief Summary: In patients with unresectable advanced pancreatic cancer, non-inferiority of TS-1 monotherapy and superiority of GEM + TS-1 combination therapy to gemcitabine (GEM) will be verified using survival time.
Detailed Description:
Minimum Age: 20 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
National Cancer Center Hospital, Tokyo, , Japan
Chung-Ho Memorial Hospital, Kaohsiung Medical University, No.100, Tzyou 1st Rd., Kaohsiung, , Taiwan
Chang Gung Memorial Hospital, Kaohsiung, No.123, Ta-Pei Rd., Niao-Sung Hsiang, Kaohsiung Hsien, , Taiwan
Changhua Christian Hospital, No.135, Nanxiao St., Changhua, , Taiwan
National Cheng Kung University Hospital, No.138, Sheng Li Road,Tainan, , Taiwan
China Medical University Hospital, No.2, Yuh-Der Rd.,Taichung, , Taiwan
Taipei Veterans General Hospital, No.201, Sec. 2, Shih-Pai road, Taipei, , Taiwan
Chi Mei Medical Center Liou Ying Campus, No.201, Taikang Village, Liou Ying Township, Tainan, , Taiwan
Chang Gung Memorial Hospital, Lonkou, No.5, Fu-Hsing St. Kuei Shan Hsiang, Taoyuan Hsien, , Taiwan
National Taiwan University Hospital, No.7, Chung San South Road, Taipei, , Taiwan
Chi Mei Medical Center, No.901, Chung Hwa Rd., Yong Kang city, Tainan, , Taiwan
Mackay Memorial Hospital, Taipei, No.92, Sec. 2, Zhongshan N. Rd., Taipei, , Taiwan
Name: Takuji Okusaka, MD
Affiliation: National Cancer Center Hospital
Role: PRINCIPAL_INVESTIGATOR