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Brief Title: Combination of Icotinib and Gemcitabine as First-line Treatment in Pancreatic Cancer
Official Title: Phase I, Open-label, Dose-escalation Study to Evaluate the Safety and Tolerability of Icotinib Combined With Gemcitabine as First-line Treatment in Locally Advanced, Unresectable or Metastatic Pancreatic Cancer
Study ID: NCT02024633
Brief Summary: Research Hypothesis: icotinib administered in combination with gemcitabine has an acceptable safety profile in subjects with locally advanced, unresectable or metastatic pancreatic adenocarcinoma.The primary objective is to determine the safety profile of icotinib in combination with gemcitabine in subjects with locally advanced, unresectable or metastatic pancreatic adenocarcinoma.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Second Affiliated Hospital of Zhejiang Univercity School of Medcine, Hangzhou, , China
Name: Tingbo Liang, MD
Affiliation: Second Affiliated Hospital of Zhejiang Univercity School of Medcine
Role: PRINCIPAL_INVESTIGATOR