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Brief Title: A Study of Volociximab in Combination With Gemcitabine in Metastatic Pancreatic Cancer
Official Title: Phase 2 Open-Label Study of Volociximab (M200) in Combination With Gemcitabine in Patients With Metastatic Pancreatic Cancer Not Previously Treated With Chemotherapy
Study ID: NCT00401570
Brief Summary: This clinical trial is being conducted to determine tumor response and preliminary safety of a monoclonal antibody that specifically binds to a cell surface receptor (α5β1 integrin) that is required for the establishment of new blood vessels during tumor growth, a process known as angiogenesis.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Site Reference ID/Investigator# 70538, Pittsburgh, Pennsylvania, United States
Site Reference ID/Investigator# 70537, Nashville, Tennessee, United States
Site Reference ID/Investigator# 70534, Glasgow, , United Kingdom
Site Reference ID/Investigator# 70533, Leeds, , United Kingdom
Site Reference ID/Investigator# 70536, Manchester, , United Kingdom
Site Reference ID/Investigator# 70535, Northwood, , United Kingdom
Name: Mihail Obrocea, MD
Affiliation: AbbVie
Role: STUDY_DIRECTOR