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Spots Global Cancer Trial Database for Alpha Radiation Emitters Device for the Treatment of Advanced Pancreatic Cancer

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Trial Identification

Brief Title: Alpha Radiation Emitters Device for the Treatment of Advanced Pancreatic Cancer

Official Title: A Feasibility and Safety Study of Intratumoral Diffusing Alpha Radiation Emitters on Advanced Pancreatic Cancer

Study ID: NCT04002479

Study Description

Brief Summary: A unique approach for cancer treatment employing intratumoral diffusing alpha radiation emitter device for advanced pancreatic cancer.

Detailed Description: This is a prospective, single-center, open label, single arm study. The study is designed to evaluate the feasibility, safety and preliminary efficacy of intratumoral alpha radiation mediated treatment with Alpha DaRT seeds for the treatment of advanced pancreatic cancer. The study will be comprised of a screening period, DaRT insertion visit, acute follow-up phase of 4-6 weeks and a long-term follow up phase of 24 months. The total duration of the study will be 24 months from the DaRT insertion procedure. 30 patients with advanced pancreatic cancer will be recruited by the investigational site. Eligible patients who meet inclusion/exclusion criteria (as assessed during the screening period) will be invited to the site for the procedure of DaRT seeds insertion. The patients will be monitored for a period of 24 months post insertion.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Centre Hospitalier de l'Université de Montréal (CHUM), Montréal, Quebec, Canada

Jewish General Hospital, Montréal, Quebec, Canada

Contact Details

Name: David Donath, MD

Affiliation: Brachytherapy Service Centre Hospitalier de l'Université de Montreal

Role: PRINCIPAL_INVESTIGATOR

Name: Corey Miller, MD

Affiliation: Division of Gastroenterology, Jewish General Hospital

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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