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Brief Title: A Study of Avastin (Bevacizumab) Added to a Chemotherapeutic Regimen in Patients With Metastatic Pancreatic Cancer
Official Title: A Randomized, Double-blind Study of the Effect of Avastin Plus Gemcitabine and Erlotinib Compared With Placebo Plus Gemcitabine and Erlotinib on Overall Survival in Patients With Metastatic Pancreatic Cancer
Study ID: NCT01214720
Brief Summary: This study will evaluate efficacy, safety and tolerability of Avastin versus placebo added to a chemotherapeutic regimen in patients with metastatic pancreatic cancer. The anticipated time of study treatment is until confirmed evidence of disease progression, and the target sample size is 500+ individuals.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
, Adelaide, , Australia
, Camperdown, , Australia
, Footscray, , Australia
, Heidelberg, , Australia
, Kurralta Park, , Australia
, Melbourne, , Australia
, Melbourne, , Australia
, St. Leonards, , Australia
, Sydney, , Australia
, Sydney, , Australia
, Graz, , Austria
, Innsbruck, , Austria
, Salzburg, , Austria
, Wien, , Austria
, Antwerpen, , Belgium
, Bruxelles, , Belgium
, Bruxelles, , Belgium
, Leuven, , Belgium
, Wilrijk, , Belgium
, Edmonton, Alberta, Canada
, Vancouver, British Columbia, Canada
, Ottawa, Ontario, Canada
, Toronto, Ontario, Canada
, Montreal, Quebec, Canada
, Quebec City, Quebec, Canada
, Beijing, , China
, Beijing, , China
, Shanghai, , China
, Brno, , Czech Republic
, Hradec Kralove, , Czech Republic
, Helsinki, , Finland
, Besancon, , France
, Bordeaux, , France
, Boulogne-billancourt, , France
, Clichy, , France
, Limoges, , France
, Marseille, , France
, Paris, , France
, Paris, , France
, Rouen, , France
, Saint Herblain, , France
, Strasbourg, , France
, Berlin, , Germany
, Bochum, , Germany
, Bonn, , Germany
, Halle, , Germany
, Hamburg, , Germany
, Heidelberg, , Germany
, Leipzig, , Germany
, Magdeburg, , Germany
, Mainz, , Germany
, Muenchen, , Germany
, Mönchengladbach, , Germany
, Trier, , Germany
, Kfar Saba, , Israel
, Petach Tikva, , Israel
, Rehovot, , Israel
, Tel Aviv, , Israel
, Bergamo, , Italy
, Bologna, , Italy
, Brescia, , Italy
, Chieti, , Italy
, Genova, , Italy
, Napoli, , Italy
, Orbassano, , Italy
, Parma, , Italy
, San Giovanni Rotondo, , Italy
, Amsterdam, , Netherlands
, Auckland, , New Zealand
, Christchurch, , New Zealand
, Lima, , Peru
, Lima, , Peru
, Gliwice, , Poland
, Lublin, , Poland
, Szczecin, , Poland
, Wroclaw, , Poland
, Singapore, , Singapore
, Singapore, , Singapore
, Cape Town, , South Africa
, Pretoria, , South Africa
, Alicante, , Spain
, Barcelona, , Spain
, Barcelona, , Spain
, Barcelona, , Spain
, Barcelona, , Spain
, Cordoba, , Spain
, Elche, , Spain
, Madrid, , Spain
, Santander, , Spain
, Valencia, , Spain
, Valencia, , Spain
, Stockholm, , Sweden
, Kueishan, , Taiwan
, Taipei, , Taiwan
, Glasgow, , United Kingdom
, Leicester, , United Kingdom
, London, , United Kingdom
, Manchester, , United Kingdom
, Northwood, , United Kingdom
, Sutton, , United Kingdom
, Truro, , United Kingdom
Name: Clinical Trials
Affiliation: Hoffmann-La Roche
Role: STUDY_DIRECTOR