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Brief Title: Pilot Study Evaluating Broccoli Sprouts in Advanced Pancreatic Cancer [POUDER Trial]
Official Title: Pilot Study Evaluating Broccoli Sprouts in Advanced Pancreatic Cancer [POUDER Trial]
Study ID: NCT01879878
Brief Summary: The goal of the POUDER trial is to determine the feasibility of a randomized controlled trial regarding the application of freeze-dried broccoli sprouts rich in sulforaphane and quercetin in patients with advanced pancreatic ductal adenocarcinoma that receive palliative chemotherapy.
Detailed Description: Patients will be randomly classified into two groups - verum and placebo. The patients in the experimental arm will receive capsules with broccoli sprout grain containing a total of 90mg sulforaphane active substance per day over one year as nutrition supplement whereas patients assigned to the placebo group will receive inactive substance (methylcellulose) with identical capsule and portion distribution.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Dept. of General and Transplant Surgery, University Hospital of Heidelberg, Germany, Heidelberg, , Germany
Name: Peter Schemmer, Prof. Dr. med.
Affiliation: Heidelberg University
Role: STUDY_DIRECTOR
Name: Ingrid Herr, Prof. Dr.
Affiliation: Heidelberg University
Role: PRINCIPAL_INVESTIGATOR