Spots Global Cancer Trial Database for Novel Controlled Hypo-Perfusion Technique in Partial Nephrectomy
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Trial Identification
Brief Title: Novel Controlled Hypo-Perfusion Technique in Partial Nephrectomy
Official Title: A Pilot Study to Examine a Novel Controlled Hypo-Perfusion Technique in Partial Nephrectomy
Study ID: NCT01720693
Interventions
Study Description
Brief Summary: Many patients who are candidates for nephron-sparing surgery, partial nephrectomy is now the standard treatment with a surgical, small, clinical T1 tumor (\<7 cm). In many recent studies, partial nephrectomy provides equivalent oncologic, and superior functional, outcomes compared with the standard radical nephrectomy over the short and long term (2, 3). Partial nephrectomy techniques, whether open, laparoscopic or robotic, typically involve hilar clamping, which creates the desired bloodless operative field, allowing for more precise tumor excision and renal reconstruction. This hilar clamping eventually may lead to ischemic kidney injury which can compromise the functional outcomes of the remaining kidney.We are working now to develop a novel technique of Hypo-Perfusion by achieving partial renal arterial clamping, with the goal of completely eliminating surgical ischemia to the renal remnant.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
University Health Network, Toronto, Ontario, Canada
Contact Details
Name: Michael Jewett, M.D.
Affiliation: University Health Network, Toronto
Role: PRINCIPAL_INVESTIGATOR
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