Spots Global Cancer Trial Database for Beat Childhood Cancer Specimen Banking and Data Registry
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Trial Identification
Brief Title: Beat Childhood Cancer Specimen Banking and Data Registry
Official Title: Specimen Banking With Clinical and Genomic Data Registry With the Establishment of Tumor Models for Pediatric Cancers
Study ID: NCT04715178
Conditions
Interventions
Study Description
Brief Summary: This is an observational data registry study of all pediatric cancer patients at Atrium Health (AH) and participating Beat Childhood Cancer Consortium sites involving specimen banking and data collection.
Detailed Description: This observational registry and banking study is being performed on a large cohort of patients who have been identified to receive molecular testing to better understand the relationship between genomic and molecular information and clinical outcomes, enabling timely and informed treatment decisions by physicians for cancer patients. We hypothesize that large gene panels, sequencing (DNA/RNA), and epigenetics of tumors can identify molecular aberrations in tumors that can be leveraged to offer more effective treatment. Findings may suggest additional research will be required to better understand the molecular underpinnings of the relationship between molecular abnormalities and disease. Banked specimens and the creation of tumor cell lines and xenograft models will enable this research to be performed.
Keywords
Eligibility
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Arkansas Children's Hospital, Little Rock, Arkansas, United States
St. Joseph's Children's Hospital, Tampa, Florida, United States
Children's Mercy Hospitals and Clinics, Kansas City, Missouri, United States
Levine Children's Hospital, Charlotte, North Carolina, United States
Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States
Randall Children's Hospital, Portland, Oregon, United States
Penn State Milton S. Hershey Medical Center and Children's Hospital, Hershey, Pennsylvania, United States
Medical University of South Carolina, Charleston, South Carolina, United States
Dell Children's Blood and Cancer Center, Austin, Texas, United States
Children's Hospital of The King's Daughters, Norfolk, Virginia, United States
Contact Details
Name: Giselle Sholler, MD
Affiliation: Beat Childhood Cancer at Atrium Health
Role: STUDY_CHAIR
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