Spots Global Cancer Trial Database for Metabolomic Analysis of Body Fluid of Medulloblastoma in Children
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Trial Identification
Brief Title: Metabolomic Analysis of Body Fluid of Medulloblastoma in Children
Official Title: Metabolomic Analysis of Body Fluid of Medulloblastoma in Children Based on New Mass Spectrometry and Its Application in Clinical Diagnosis and Recurrence Monitoring
Study ID: NCT04065204
Conditions
Interventions
Study Description
Brief Summary: Based on a new mass spectrometry system, body fluid samples were analyzed to verify the role of metabolite analysis in the diagnosis of pediatric medulloblastoma.
Detailed Description: Screening specific molecular metabolic markers for medulloblastoma after radiotherapy can improve the prediction of clinical diagnosis and prognosis of patients.The purpose of this study is to validate the role of metabolite analysis in the diagnosis of pediatric medulloblastoma based on the analysis of body fluid samples by a new mass spectrometry system.Based on the metabolic markers found by screening, the pathogenic mechanism of metabolic pathway blockade was explained, and the scientific basis for later treatment was put forward.
Eligibility
Minimum Age: 3 Years
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
The Department of Radiation Oncology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, Shanghai, China
Contact Details
Name: Mawei D Jiang, MD
Affiliation: Xin Hua Hospital affiliated to Shanghai Jiaotong University School of Medicine
Role: PRINCIPAL_INVESTIGATOR
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