Spots Global Cancer Trial Database for Transplantation After Complete Response In Patients With T-cell Lymphoma
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
Trial Identification
Brief Title: Transplantation After Complete Response In Patients With T-cell Lymphoma
Official Title: Transplantation After Complete Response In Patients With T-cell Lymphoma
Study ID: NCT05444712
Conditions
Study Description
Brief Summary: Peripheral T-cell lymphoma (PTCL) encompasses a broad range of post-thymic (i.e., mature) sub-entities as defined by the 2017 WHO classification. The most common entities are angioimmunoblastic T-cell lymphoma (AITL) and other Tfh-phenotype PTCL or PTCL not otherwise specified (NOS), each representing approximately 20 to 25% of mature T- and NK/T-cell lymphomas. Compared to their B-cell counterparts, most PTCL confer dismal prognosis. In fact, except for anaplastic lymphoma kinase (ALK)-positive systemic anaplastic large cell lymphoma (sALCL), 10-year overall survival for patients with PTCL barely exceeds 30%. Given the infrequency and the heterogeneity of these malignancies, no real consensus on first-line treatment has been established for most PTCL. The place of autologous stem cell transplantation (ASCT) as a consolidation procedure for patients with PTCL achieving a complete metabolic response after induction is still highly debated. ESMO recommendations and recent guidelines from a committee of the American Society for Blood and Marrow Transplantation currently propose ASCT as first-line therapy for transplant-eligible patients for all patients reaching at least a partial response (PR) after induction. NCCN guidelines (version 2.2017) recommend ASCT or observation in case of metabolic CR but salvage regimen in case of residual disease after induction.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Chu D'Amiens - Hopital Sud, Amiens, , France
Chu D'Angers, Angers, , France
Ch Victor Dupouy, Argenteuil, , France
Ch D'Avignon - Hopital Henri Duffaut, Avignon, , France
Ch de La Cote Basque, Bayonne, , France
Service d'Onco-radiolothérapie, Polyclinique Bordeaux Nord Aquitaine, Bordeaux, , France
Ch Metropole Savoie - Site Chambery, Chambéry, , France
Chu Estaing, Clermont-Ferrand, , France
Ch Alpes Leman, Contamine sur Arve, , France
Hopital Henri Mondor, Creteil, , France
René Olivier Casasnovas, Dijon, , France
CHU Francois MITTERRAND, Dijon, , France
Ch de Dunkerque, Dunkerque, , France
Chd de Vendee, La Roche-sur-Yon, , France
Ch de Versailles - Hopital Andre Mignot, Le Chesnay, , France
CHU du Mans, Le Mans, , France
Service Oncologie médicale, HOPITAL SAINT VINCENT-DE-PAUL, Lille, , France
Service Hématologie Clinique et Thérapie Cellulaire, CHU DE LIMOGES - HOPITAL DUPUYTREN,, Limoges, , France
Centre Leon Berard, Lyon, , France
Chu de Montpellier, Montpellier, , France
Chu de Nantes, Nantes, , France
Centre Antoine Lacassagne, Nice, , France
Chu de Nimes - Hopital Caremeau, Nîmes, , France
Chr Orleans, Orléans, , France
Hopital Cochin, Paris, , France
Hopital de La Pitie Salpetriere, Paris, , France
Hopital Necker, Paris, , France
Hopital Saint Antoine, Paris, , France
Ch de Perpignan, Perpignan, , France
Chu de Bordeaux - Hopital Haut-Leveque, Pessac, , France
Chu Lyon-Sud, Pierre Benite, , France
Ch Annecy Genevois, Pringy, , France
Ch Perigueux, Périgueux, , France
Chu Pontchaillou_Rennes, Rennes, , France
Ch de Roubaix - Hopital Victor Provo, Roubaix, , France
Centre Henri Becquerel, Rouen, , France
Service Hématologie, Institut Curie - Hôpital René HUGUENIN, Saint-Cloud, , France
Chu de La Reunion - Hopital Felix Guyon, Saint-Denis, , France
Chu de La Reunion - Ghsr, Saint-Pierre, , France
Institut Cancerologie & Hematologie St-Etienne, Saint-Priest-en-Jarez, , France
Ch de Saint-Quentin, Saint-Quentin, , France
Hôpitaux Universitaires de Strasbourg, Strasbourg, , France
Institut Universitaire du Cancer, Toulouse, , France
Chu Bretonneau, Tours, , France
Ch de Valence, Valence, , France
Ch de Valenciennes - Hopital Jean Bernard, Valenciennes, , France
Chu Brabois, Vandœuvre-lès-Nancy, , France
Institut Gustave Roussy, Villejuif, , France
Contact Details
Name: Emmanuel BACHY, Pr
Affiliation: HCL
Role: PRINCIPAL_INVESTIGATOR
Take Control of Your Skin and Body Changes Today.
Try out Spots for free, set up only takes 2 mins.
Join others from around the world:
