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Brief Title: Lenalidomide, Vorinostat and Dexamethasone in Relapsed Patients With Peripheral T-Cell Non-Hodgkin's Lymphoma (PTCL)
Official Title: Phase I/II Trial of Lenalidomide in Combination With Vorinostat and Dexamethasone as Therapy in Relapsed or Refractory Patients With Peripheral T-Cell Non-Hodgkin's Lymphoma (PTCL)
Study ID: NCT00972842
Brief Summary: A standard therapy is neither established in first-line patients nor in relapsed patients with PTCL, and there is still an unmet medical need to identify novel efficacious and safe therapy regimens. The aim of this study is to evaluate the potential of a Lenalidomide plus Vorinostat and Dexamethasone combination therapy as an effective and safe therapeutic regimen, in the treatment of relapsed PTCL following failure of prior regimens.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Medizinische Universitaet Innsbruck, Abtlg. f. Haematologie und Onkologie, Innsbruck, Tirol, Austria
Krankenhaus der Elisabethinen Linz, Linz, , Austria
Krankenhaus der Stadt Linz, Linz, , Austria
Universitaetsklinik f. Innere Medizin III, Salzburg, , Austria
Hanusch Krankenhaus, Vienna, , Austria
Name: Georg Hopfinger, MD
Affiliation: Hanusch Krankenhaus Wien
Role: PRINCIPAL_INVESTIGATOR