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Brief Title: Ultrasound Guided Pectoral Nerves Blockade for Persistent Pain After Breast Cancer Surgery
Official Title: Ultrasound Guided Pectoral Nerves (Pecs) Blockade in Persistent Pain After Breast Cancer Surgery
Study ID: NCT02349581
Brief Summary: This is a pilot study of the pectoral nerves block (PECS) in patients with persistent pain after breast cancer surgery.
Detailed Description: This study is in 2 parts: Part 1 is a description of the anatomy of the PECS block in pain free, unoperated patients using ultrasonography (non invasive). Part 2 is the administration of the block to patients that have persistent pain after breast cancer surgery. Before and after the block we will take a detailed pain history and do neurophysiological tests called quantitative sensory testing (QST). These tests assess the patients' ability to feel warmth, cold and test their thresholds for pain. The block is then administered using ultrasound guidance and 20mls of 0.25% bupivacaine is injected in the pectoral muscles on the side with pain. Thirty minutes after the block, the pain is re assessed and the QST is repeated.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Section for surgical pathophysiology 7621 Rigshospitalet, Copenhagen, Sjaelland, Denmark
Name: Henrik Kehlet, MD, PhD, DMsc
Affiliation: Rigshospitalet, Denmark
Role: STUDY_DIRECTOR