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Brief Title: Nasal Outcomes Using Saline Irrigations After Endonasal Pituitary Surgery
Official Title: Nasal Outcomes Using Saline Irrigations After Endonasal Pituitary Surgery - The NOSE Trial
Study ID: NCT05659524
Brief Summary: This is a prospective, single-blinded, multicenter study evaluating the benefit of sinonasal irrigations following endoscopic pituitary surgery. The goal of this study is to create practice changing guidelines with objective data highlighting the importance of irrigations on postoperative outcomes for pituitary surgery.
Detailed Description: This prospective study, coupled with the results of the recent POET study evaluating the role of antibiotics in postoperative outcomes for pituitary surgery, will guide physicians in the optimal management of patients following endoscopic pituitary surgery. The investigator group has an established record of completing multicenter studies (e.g., POET, TRANSPHER) that have influenced clinical practice guidelines, raised the profile of Barrow in the pituitary and skull base community, and resulted in numerous peer-reviewed publications and awards.
Minimum Age: 19 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Barrow Neurological Institute at St. Joseph's Hospital and Medical Center, Phoenix, Arizona, United States
Cleveland Clinic, Cleveland, Ohio, United States