Spots Global Cancer Trial Database for SC Versus IV Isatuximab in Combination With Pomalidomide and Dexamethasone in RRMM
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
Trial Identification
Brief Title: SC Versus IV Isatuximab in Combination With Pomalidomide and Dexamethasone in RRMM
Official Title: A Randomized, Phase 3, Open Label Study Evaluating Subcutaneous Versus Intravenous Administration of Isatuximab in Combination With Pomalidomide and Dexamethasone in Adult Patients With Relapsed and/or Refractory Multiple Myeloma (RRMM)
Study ID: NCT05405166
Conditions
Study Description
Brief Summary: This is a randomized, multicenter, Phase 3, open-label study evaluating subcutaneous (SC) vs intravenous (IV) administration of isatuximab in combination with pomalidomide and dexamethasone (Pd) in RRMM patients (study participants) who have received at least 1 prior line of therapy including lenalidomide and a proteasome inhibitor (PI). Eligible participants will be randomized 1:1 into 1 of 2 study arms: Arm SC: Isatuximab SC + Pd Arm IV: Isatuximab IV + Pd Participants will be allowed to continue therapy until disease progression, unacceptable adverse events (AEs), participant request to discontinue therapy or any other reason, whichever comes first.
Detailed Description: Two study arms will be treated in 4-week cycles until disease progression, unacceptable adverse events (AEs), participant request to discontinue therapy or any other reason, whichever comes first.
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Mohtaseb Cancer Center and Blood Disorders Site Number : 8400028, Bullhead City, Arizona, United States
Arizona Oncology Associates, PC - HAL Site Number : 8400015, Prescott Valley, Arizona, United States
Rocky Mountain Cancer Centers, LLP Site Number : 8400021, Aurora, Colorado, United States
Mayo Clinic Site Number : 8400008, Jacksonville, Florida, United States
BRCR Medical Center Inc Site Number : 8400030, Plantation, Florida, United States
Centre for Cancer and Blood Disorders Site Number : 8400026, Bethesda, Maryland, United States
Hattiesburg Clinic Site Number : 8400006, Hattiesburg, Mississippi, United States
Comprehensive Cancer Centers of Nevada Site Number : 8400019, Las Vegas, Nevada, United States
Atlantic Health System Site Number : 8400005, Morristown, New Jersey, United States
New York Oncology Hematology, P.C. Site Number : 8400017, Albany, New York, United States
Novant Health Site Number : 8400014, Charlotte, North Carolina, United States
Novant Health Forsyth Medical Center Site Number : 8400114, Winston-Salem, North Carolina, United States
Gabrail Cancer Center Site Number : 8400027, Canton, Ohio, United States
Oncology_Hematology Care Clinical Trials, LLC Site Number : 8400016, Cincinnati, Ohio, United States
Oncology Associates Of Oregon, P.C. Site Number : 8400018, Eugene, Oregon, United States
Spoknwrd Clinical Trials Inc. Site Number : 8400023, Easton, Pennsylvania, United States
Gibbs Cancer Center-Spartanburg Medical Center Site Number : 8400002, Spartanburg, South Carolina, United States
Texas Oncology Baylor Sammons Site Number : 8400022, Dallas, Texas, United States
Lumi Research Site Number : 8400029, Kingwood, Texas, United States
Texas Oncology - San Antonio Site Number : 8400020, San Antonio, Texas, United States
George E. Wahlen Salt Lake City VA Medical Center Site Number : 8400011, Salt Lake City, Utah, United States
UW Cancer Center at ProHealth Care Site Number : 8400001, Waukesha, Wisconsin, United States
Investigational Site Number : 0320007, Caba, Buenos Aires, Argentina
Investigational Site Number : 0320001, Caba, Buenos Aires, Argentina
Investigational Site Number : 0320002, Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina
Investigational Site Number : 0320006, La Plata, Buenos Aires, Argentina
Investigational Site Number : 0320003, Caba, Ciudad De Buenos Aires, Argentina
Investigational Site Number : 0320008, Caba, Ciudad De Buenos Aires, Argentina
Investigational Site Number : 0320005, Caba, Ciudad De Buenos Aires, Argentina
Investigational Site Number : 0320010, Cordoba, Córdoba, Argentina
Investigational Site Number : 0320004, Buenos Aires, , Argentina
Investigational Site Number : 0320009, Mendoza, , Argentina
Investigational Site Number : 0360007, Liverpool, New South Wales, Australia
Investigational Site Number : 0360004, Waratah, New South Wales, Australia
Investigational Site Number : 0360003, Wollongong, New South Wales, Australia
Investigational Site Number : 0360008, Adelaide, South Australia, Australia
Investigational Site Number : 0360009, Fitzroy, Victoria, Australia
Investigational Site Number : 0360006, Melbourne, Victoria, Australia
Investigational Site Number : 0360001, Richmond, Victoria, Australia
NOHC - Nucleo de Oncologia e Hematologia do Ceara Site Number : 0760006, Fortaleza, Ceará, Brazil
OC ONCOCLINICAS MULTIHEMO ILHA DO LEITE Site Number : 0760007, Recife, Pernambuco, Brazil
CHN - Complexo Hospitalar de Niteroi Site Number : 0760008, Niteroi, Rio De Janeiro, Brazil
Hospital Mae de Deus Site Number : 0760003, Porto Alegre, Rio Grande Do Sul, Brazil
A Beneficencia Portuguesa de Sao Paulo - Hospital Beneficencia Portuguesa - BP Mirante Site Number : 0760002, Sao Paulo, São Paulo, Brazil
Clínica São Germano Site Number : 0760001, Sao Paulo, São Paulo, Brazil
Instituto COI de Educacao e Pesquisa Site Number : 0760004, Rio De Janeiro, , Brazil
Investigational Site Number : 1240001, Toronto, Ontario, Canada
Investigational Site Number : 1240004, Greenfield Park, Quebec, Canada
Investigational Site Number : 1240003, Montreal, Quebec, Canada
Investigational Site Number : 1520002, Santiago, Reg Metropolitana De Santiago, Chile
Investigational Site Number : 1520003, Santiago, Reg Metropolitana De Santiago, Chile
Investigational Site Number : 1520006, Santiago, Reg Metropolitana De Santiago, Chile
Investigational Site Number : 1520005, Viña del Mar, Valparaíso, Chile
Investigational Site Number : 1520004, Santiago, , Chile
Investigational Site Number : 1520001, Temuco, , Chile
Investigational Site Number : 1560001, Beijing, , China
Investigational Site Number : 1560022, Beijing, , China
Investigational Site Number : 1560010, Changsha, , China
Investigational Site Number : 1560006, Guangzhou, , China
Investigational Site Number : 1560002, Hangzhou, , China
Investigational Site Number : 1560020, Nanchang, , China
Investigational Site Number : 1560019, Nanning, , China
Investigational Site Number : 1560011, Qingdao, , China
Investigational Site Number : 1560017, Shanghai, , China
Investigational Site Number : 1560013, Shenyang, , China
Investigational Site Number : 1560021, Shenzhen, , China
Investigational Site Number : 1560007, Tianjin, , China
Investigational Site Number : 1560009, Tianjin, , China
Investigational Site Number : 1560018, Tianjin, , China
Investigational Site Number : 1560003, Wuhan, , China
Investigational Site Number : 1560008, Wuhan, , China
Investigational Site Number : 1560004, Zhengzhou, , China
Investigational Site Number : 2030005, Brno, , Czechia
Investigational Site Number : 2030003, Olomouc, , Czechia
Investigational Site Number : 2030006, Ostrava - Poruba, , Czechia
Investigational Site Number : 2030004, Praha 2, , Czechia
Investigational Site Number : 2500006, Lyon, , France
Investigational Site Number : 2500002, Nantes, , France
Investigational Site Number : 2500005, Paris, , France
Investigational Site Number : 2500008, Perigueux, , France
Investigational Site Number : 2500004, Pierre Benite, , France
Investigational Site Number : 2500001, Poitiers, , France
Investigational Site Number : 2500009, Saint-Etienne Cedex 2, , France
Investigational Site Number : 2500003, TOULOUSE Cedex 9, , France
Investigational Site Number : 2500007, Tours, , France
Investigational Site Number : 2760005, Dresden, , Germany
Investigational Site Number : 2760001, Hamburg, , Germany
Investigational Site Number : 2760003, Heidelberg, , Germany
Investigational Site Number : 2760006, Lübeck, , Germany
Investigational Site Number : 2760007, Nürnberg, , Germany
Investigational Site Number : 3000002, Athens, , Greece
Investigational Site Number : 3000001, Athens, , Greece
Investigational Site Number : 3000005, Ioannina, , Greece
Investigational Site Number : 3000003, Patra, , Greece
Investigational Site Number : 3000004, Thessaloniki, , Greece
Investigational Site Number : 3480002, Budapest, , Hungary
Investigational Site Number : 3480004, Budapest, , Hungary
Investigational Site Number : 3480003, Kaposvár, , Hungary
Investigational Site Number : 3480008, Pécs, , Hungary
Investigational Site Number : 3480005, Szekesfehervar, , Hungary
Investigational Site Number : 3480006, Szombathely, , Hungary
Investigational Site Number : 3800001, Meldola, Forlì-Cesena, Italy
Investigational Site Number : 3800004, Ancona, , Italy
Investigational Site Number : 3800002, Bologna, , Italy
Investigational Site Number : 3800005, Brescia, , Italy
Investigational Site Number : 3800007, Napoli, , Italy
Investigational Site Number : 3800008, Palermo, , Italy
Investigational Site Number : 3800003, Pavia, , Italy
Investigational Site Number : 3920001, Nagoya-shi, Aichi, Japan
Investigational Site Number : 3920007, Kamogawa-shi, Chiba, Japan
Investigational Site Number : 3920005, Higashiibaraki-gun, Ibaraki, Japan
Investigational Site Number : 3920010, Shiwa-gun, Iwate, Japan
Investigational Site Number : 3920012, Kamakura-shi, Kanagawa, Japan
Investigational Site Number : 3920003, Kyoto-shi, Kyoto, Japan
Investigational Site Number : 3920006, Natori-shi, Miyagi, Japan
Investigational Site Number : 3920002, Okayama-shi, Okayama, Japan
Investigational Site Number : 3920011, Osaka-shi, Osaka, Japan
Investigational Site Number : 3920008, Sunto-gun, Shizuoka, Japan
Investigational Site Number : 3920004, Shibuya-ku, Tokyo, Japan
Investigational Site Number : 3920009, Yamagata-shi, , Japan
Investigational Site Number : 5780001, Oslo, , Norway
Investigational Site Number : 5780002, Ålesund, , Norway
Investigational Site Number : 6160004, Wroclaw, Dolnoslaskie, Poland
Investigational Site Number : 6160005, Krakow, Malopolskie, Poland
Investigational Site Number : 6160001, Lublin, , Poland
Investigational Site Number : 6160003, Wroclaw, , Poland
Investigational Site Number : 7240003, Santander, Cantabria, Spain
Investigational Site Number : 7240004, Badalona, Catalunya [Cataluña], Spain
Investigational Site Number : 7240007, Madrid, Madrid, Comunidad De, Spain
Investigational Site Number : 7240001, Pamplona, Navarra, Spain
Investigational Site Number : 7240005, Madrid, , Spain
Investigational Site Number : 7240006, Murcia, , Spain
Investigational Site Number : 7240002, Salamanca, , Spain
Investigational Site Number : 7520001, Borås, , Sweden
Investigational Site Number : 7520002, Stockholm, , Sweden
Investigational Site Number : 7520003, Stockholm, , Sweden
Investigational Site Number : 1580001, Kaohsiung, , Taiwan
Investigational Site Number : 1580005, Tainan, , Taiwan
Investigational Site Number : 1580002, Taipei, , Taiwan
Investigational Site Number : 7920007, Ankara, , Turkey
Investigational Site Number : 7920009, Ankara, , Turkey
Investigational Site Number : 7920004, Bornova, , Turkey
Investigational Site Number : 7920003, Istanbul, , Turkey
Investigational Site Number : 7920005, Istanbul, , Turkey
Investigational Site Number : 7920008, Istanbul, , Turkey
Investigational Site Number : 7920001, Istanbul, , Turkey
Investigational Site Number : 8260002, Leicester, Leicestershire, United Kingdom
Investigational Site Number : 8260005, London, London, City Of, United Kingdom
Investigational Site Number : 8260001, Norwich, Norfolk, United Kingdom
Investigational Site Number : 8260004, Birmingham, , United Kingdom
Investigational Site Number : 8260003, Derby, , United Kingdom
Contact Details
Name: Clinical Sciences & Operations
Affiliation: Sanofi
Role: STUDY_DIRECTOR
Take Control of Your Skin and Body Changes Today.
Try out Spots for free, set up only takes 2 mins.
Join others from around the world:
