Spots Global Cancer Trial Database for Phytoestrogens as an Alternative to Estradiol in Ovulation Induction in PCOS

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Trial Identification

Brief Title: Phytoestrogens as an Alternative to Estradiol in Ovulation Induction in PCOS

Official Title: Phytoestrogens as an Alternative to Estradiol in Reversing the Antiestrogenic Effect of Clomid on Endometrium in Ovulation Induction in Cases of Polycystic Ovarian Syndrome

Study ID: NCT02352597

Conditions

Polycystic Ovaries

Interventions

phytoestrogen

estradiol valerate

clomiphene citrate

Study Description

Brief Summary: Prospective study conducted on 150 women with polycystic ovarian syndrome (PCOS) were randomly divided into 3 groups: group I (50 women) received clomiphene citrate (CC) only 50 mg orally every 8 hours started from cycle day 3 for 5 days, group II (50 women) received 2mg estradiol valerate daily from cycle day 7 - 11 in addition to CC and group III (50 women) received phytoestrogen (20mg of cimifuga racemosa from day 1- 12) in addition to CC.

Detailed Description: Prospective study conducted on 150 women with PCOS were randomly divided into 3 groups: group I (50 women) received CC only50 mg orally every 8 hours started from cycle day 3 for 5 days, group II (50 women) received 2mg estradiol valerate daily from cycle day 7 - 11 in addition to CC and group III (50 women) received phytoestrogen (20mg of cimifuga racemosa from day 1- 12) in addition to CC.