Spots Global Cancer Trial Database for Novel Subtypes of Polycystic Ovary Syndrome
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Trial Identification
Brief Title: Novel Subtypes of Polycystic Ovary Syndrome
Official Title: An Evidence-Based Novel Subtypes of Polycystic Ovary Syndrome and Their Association With Outcomes: a Large Cohort Study
Study ID: NCT06124391
Conditions
Interventions
Study Description
Brief Summary: To classify subtypes of Polycystic Ovary Syndrome (PCOS) using machine-learning algorithms, and compare the reproductive and metabolic characteristics and IVF outcomes across these identified subtypes.
Detailed Description: In this study, we've developed a machine-learning model to classify PCOS patients into four subtypes based on nine clinical characteristics. The goal of this observational study is to: * Learn about different PCOS subtypes using our classification model. * Compare the reproductive and metabolic features of these subtypes. * Assess the outcomes of IVF among different PCOS subtypes. * Prospective 6.5-year follow-up data will be collected. Participants will: * Undergo a telephone interview to gather details on: 1. Current physical stats like height and weight. 2. Reproductive history, including pregnancies and childbirths in recent years. 3. Details about any IVF treatments. 4. Current status of conditions such as PCOS, Type 2 Diabetes, hypertension, and dyslipidemia. * Be invited for a physical examination that includes: 1. Measurements such as height, weight, blood pressure, and body circumferences. 2. Laboratory tests for endocrine and metabolic conditions. 3. Ultrasound scans of the ovaries and liver.
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT
Sex: FEMALE
Healthy Volunteers: Yes
Locations
Penn State College of Medicine, Hershey, Pennsylvania, United States
Hospital de Clinicas de Porto Alegre, Porto Alegre, , Brazil
Chengdu Jinjiang Maternity and Child Health Hospital, Chengdu, , China
Guangdong Second Provincial General Hospital, Guangzhou, , China
Shandong University, Jinan, , China
Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, , China
Tianjin Medical University General Hospital, Tianjin, , China
General Hospital of Ningxia Medical University, Yinchuan, , China
National University Hospital, National University of Singapore, Singapore, , Singapore
Karolinska Institutet, Solna, , Sweden
Hacettepe University School of Medicine Hacettepe, Ankara, , Turkey
Contact Details
Name: Zi-jiang Chen
Affiliation: Center for Reproductive Medicine, Shandong University
Role: STUDY_CHAIR
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