Spots Global Cancer Trial Database for Effect of Ramadan Fasting on Ovulation and Insuline Resistance in Patients With PCOS

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Trial Identification

Brief Title: Effect of Ramadan Fasting on Ovulation and Insuline Resistance in Patients With PCOS

Official Title: Does Prolonged Fasting Break the Vicious Circle of Polycystic Ovarian Syndrome of Insulin Resistance ?

Study ID: NCT02499289

Conditions

Polycystic Ovary Syndrome

Interventions

Study Description

Brief Summary: Polycystic ovary syndrome (PCOS) has a heterogeneous clinical presentation comprising reproductive (hyperandrogenism, menstrual irregularity, anovulation, infertility, pregnancy complications), metabolic \[insulin resistance (IR), increased type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD) risk factors\] and psychological features (worsened quality of life and increased anxiety and depression) Whether prolonged fasting during Ramadan breaks the insulin resistance state of polycystic ovarian syndrome and subsequently improve the ovulation and spontaneous pregnancy will happen without ovarian stimulation.

Detailed Description: Question of the study: The question is raised whether prolonged fasting during Ramadan breaks the insulin resistance state of polycystic ovarian syndrome and improve the metabolic syndrome does prolonged fasting decrease glucose level, insulin level, insulin resistance markers such as adipokines and subsequently improve ovarian function and causes spontaneous ovulation.