Spots Global Cancer Trial Database for Polycystic Ovary Syndrome (PCOS): Effect Of Letrozole and Berberine
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Trial Identification
Brief Title: Polycystic Ovary Syndrome (PCOS): Effect Of Letrozole and Berberine
Official Title: Letrozole and Berberine in Infertile PCOS Patients
Study ID: NCT01116167
Conditions
Study Description
Brief Summary: Polycystic ovary syndrome (PCOS) is a heterogeneous disorder affecting almost4%-7% of the female population of reproductive age. Its heterogeneity is characterized by a wide spectrum of features, including ovulatory dysfunction and infertility, hyperandrogenism, hyperinsulinemia, insulin resistance (IR), and progression to type 2 diabetes.Since the Ming Dynasty in China,PCOS has been defined as "phlegm and wetness"infertility in traditional Chinese medicine ,namely "metabolic infertility".Chinese herbs have been used to treat PCOS for thousands of years with good effects.Berberine has also been used for diabetic patients in traditional Chinese medicine for hundreds of years. Recent studies have reported its effects on hyperglycemia and dyslipidemia.The purpose of this study is to determine whether Letrozole combined with berberine are effective in the treatment of infertile PCOS patients.
Detailed Description:
Keywords
Eligibility
Minimum Age: 20 Years
Eligible Ages: ADULT
Sex: FEMALE
Healthy Volunteers: No
Locations
Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui, China
Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China
Guangzhou Medical School First Affiliated Hospital, Guangzhou, Guangdong, China
Daqing LongNa Hospital, Daqing, Heilongjiang, China
Daqing Longnan hospital, Daqing, Heilongjiang, China
Obstetrics and Gynecology,Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China
First Affliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China
Mudanjiang maternal and children hospital, Mudanjiang, Heilongjiang, China
2nd Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan, China
First Affiliated Hospital of Hunan University of Chinese, Changsha, Hunan, China
SuqianMaternal and Child Health Hospital, Suqian, Jiangsu, China
First Hospital, Jiangxi college of Chinese Medicine, Nanchang, Jiangxi, China
Dalian Maternal and Child Health Hospital, Dalian, Liaoning, China
Shanxi Hospital of Chinese Medicine, Taiyuan, Shanxi, China
First Affiliated Hospital of Tianjin University of Chinese Medicine, Tianjin, Tianjin, China
Second Affiliated Hospital, Tianjin University of Chinese Medicine, Tianjin, Tianjin, China
Zhejiang province hospital of integrated traditional and western medicine, Hangzhou, Zhejiang, China
Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, , China
Contact Details
Name: Lihui Hou, MD.
Affiliation: The First Affliated Hospital,Heilongjiang University of Chinese Medicine .
Role: STUDY_CHAIR
Name: Xiaoke Wu, MD.PhD.
Affiliation: The First Affliated Hospital,Heilongjiang University of Chinese Medicine
Role: STUDY_CHAIR
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