Spots Global Cancer Trial Database for Follicular Fluid Raman Shifts and IVF Outcomes
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Trial Identification
Brief Title: Follicular Fluid Raman Shifts and IVF Outcomes
Official Title: The Correlation Between Follicular Fluid Raman Spectrum and Embryo Development in Infertile Patients With Polycystic Ovary Syndrome
Study ID: NCT04838535
Interventions
Study Description
Brief Summary: This study intends to collect about 150 cases of follicular fluid samples from PCOS and non-PCOS infertility patients undergoing in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) cycles (in clinical routines).We tend to detect Raman metabolic profile of the follicular fluid of the PCOS and non-PCOS groups, and find the correlation between the metabolic profile of the follicular fluid of PCOS patients and the oocyte quality, IVF outcome and subsequent embryo development are also under investigation. Metabolomics analysis was applied to look for markers of follicular fluid in PCOS patients, and further exploring data and strategies to improve the embryonic development potential and IVF outcome of PCOS patients.
Detailed Description:
Keywords
Eligibility
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: Yes
Locations
Shanghai JiAi Genetics and IVF Institute, Shanghai, Shanghai, China
Contact Details
Name: Xiaoxi Sun, Prof.
Affiliation: Shanghai JiAi Genetics & IVF Institute
Role: STUDY_CHAIR
Name: Jing Fu, Dr.
Affiliation: Shanghai JiAi Genetics & IVF Institute
Role: PRINCIPAL_INVESTIGATOR
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