Spots Global Cancer Trial Database for Metabolic Disturbances in Polycystic Ovary Syndrome (PCOS)
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Trial Identification
Brief Title: Metabolic Disturbances in Polycystic Ovary Syndrome (PCOS)
Official Title: Insulin Resistance in Polycystic Ovary Syndrome (PCOS)
Study ID: NCT00606671
Conditions
Interventions
Study Description
Brief Summary: The scope of the study was to investigate different metabolic aspects that may lead to or are a consequence of insulin resistance in premenopausal women with polycystic ovary syndrome (PCOS). We use gold standard methods for evaluation of insulin resistance. We take muscle and fat biopsies for investigation of gene expression of different cytokines associated with insulin resistance. We investigate the incretin hormones GIP and GLP-1. These two hormones play a central role in glycemic control, and diabetic subjects are known to have alterations in their incretin hormones. The incretin hormones have not previously been investigated in women with PCOS.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT
Sex: FEMALE
Healthy Volunteers: Yes
Locations
Dpt. of Obstetrics and Gynaecology, Copenhagen University Hospital, Hvidovre, Hvidovre, , Denmark
Contact Details
Name: Pernille Fog Svendsen, MD
Affiliation: Dpt. of Obstetrics and Gynaecology, Copenhagen University Hospital, Hvidovre
Role: PRINCIPAL_INVESTIGATOR
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