Spots Global Cancer Trial Database for Polycystic Ovary Syndrome and BETATROPHIN

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Trial Identification

Brief Title: Polycystic Ovary Syndrome and BETATROPHIN

Official Title: Can the Betatrophin be a Reliable Marker of Insulin Resistance in Normal Weight and Overweight Women With Polycystic Ovary Syndrome?

Study ID: NCT04448730

Conditions

Polycystic Ovary

Obesity

Interventions

serum marker levels

Study Description

Brief Summary: This is an original study giving an information about the association body mass index, polycystic ovary syndrome and betatrophin.

Detailed Description: Introduction: Betatrophin is a protein hormone which has a significant role in glucose homeostasis and lipid metabolism. The aim of this study is to compare the levels of serum betatrophin in overweight and normal weight women with PCOS. Material and Method: Thirty-five patients normal weight women with PCOS (BMI\<25) and 38 obese women with PCOS (BMI≥25) were included in this prospective, cross-sectional study. Patients were selected according to Rotterdam criteria. Serum betatrophin levels were studied by ELISA method and then compared between these two groups besides the following additional parameters as waist circumference/hip circumference ratio, fasting blood glucose, 75 g OGTT (oral glucose tolerance test) results and HOMA-IR levels.