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Brief Title: A Phase 1 Study of XL019 in Adults With Polycythemia Vera
Official Title: A Phase 1 Dose-Escalation Study of the Safety, Pharmacokinetics, and Pharmacodynamics of XL019 Administered to Subjects With Polycythemia Vera
Study ID: NCT00595829
Brief Summary: The purpose of this study is to evaluate the safety and tolerability of the JAK2 inhibitor XL019 administered orally in adults with Polycythemia Vera.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
UCLA School of Medicine, Center for Health Sciences, Los Angeles, California, United States
UCSF - Division of Hematology/Oncology, San Francisco, California, United States
H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, United States
University of Michigan Health System, Ann Arbor, Michigan, United States
Weill Cornell Medical College, New York, New York, United States