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Brief Title: Familial Myeloproliferative Disorders
Official Title: Molecular Biology of Familial Myeloproliferative Disorders
Study ID: NCT00666289
Brief Summary: Myeloproliferative disorders occur in families, thus giving rise to the theory that it is a genetic disease that may be caused by an abnormal gene in the DNA that can be passed from one generation of family members to another. DNA can be gathered from family members through blood samples and the investigators will investigate (through DNA testing) to see if there are abnormal genes that may be responsible for causing the MPDs. Understanding which genes are responsible for causing MPDs can help develop ways to identify people who may be at risk for developing an MPD, allow for the development of better treatments, possibly a cure, or even prevent the development of MPDs.
Detailed Description:
Minimum Age: 7 Years
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Georgetown University, Washington, D.C., District of Columbia, United States
University of Illinois at Chicago, Chicago, Illinois, United States
Mount Sinai School of Medicine, New York, New York, United States
Weill Cornell, New York, New York, United States
University of Utah, Salt Lake City, Utah, United States
University of Florence, Florence, , Italy
Name: Josef Prachal, MD
Affiliation: Myeloproliferative Disorders-Research Consortium
Role: STUDY_CHAIR