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Brief Title: The Efficacy of Using Pentoxifylline in Patients Undergoing Breast Cancer Surgery
Official Title: The Efficacy of Pentoxifylline in Reducing Post-surgical Complications in Patients Undergoing Breast Cancer Surgery
Study ID: NCT06087237
Brief Summary: The goal of this clinical trial is to assess the efficacy of pentoxifylline in reducing post surgical complications for breast cancer patients undergoing breast cancer surgery. It aims to evaluate the efficacy of pentoxifylline on postoperative pain and wound healing. Participants will take oral pentoxifylline then post surgical oral pentoxifylline three times per day for 2 weeks. The researchers will compare the difference in pain score and wound healing relative to the control group.
Detailed Description: The goal of this clinical trial is to assess the efficacy of pentoxifylline in reducing post surgical complications for breast cancer patients undergoing mastectomy. It aims to evaluate the efficacy of adjuvant pentoxifylline in reducing postoperative pain and improving wound healing in breast cancer patients undergoing mastectomy surgery. Participants will take oral oral pentoxifylline 400 mg three times per day 400 mg three times for the day before surgery then oral pentoxifylline 400 mg three times per day for 2 weeks while the control group will take placebo tablet one day before surgey and placebo tablets three times per day for 2 weeks after surgery. the researchers will compare the difference in pain score and time for wound healing relatively to the control group.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Oncology center of Mansoura University, Mansoura, , Egypt
Name: Samar A. Dewidar, MSc
Affiliation: clinical pharmacy and pharmacy practice department, Faculty of pharmacy, Mansoura University
Role: STUDY_CHAIR
Name: Noha O. Mansour, PhD
Affiliation: Clinical pharmacy and pharmacy practice department, Faculty of pharmacy, Mansoura University
Role: STUDY_DIRECTOR
Name: Moetaza M. Soliman, PhD
Affiliation: Clinical pharmacy and pharmacy practice department, Faculty of pharmacy, Mansoura University
Role: STUDY_DIRECTOR
Name: Mohamed A. Shams, PhD
Affiliation: Clinical pharmacy and pharmacy practice department, Faculty of pharmacy, Mansoura University
Role: STUDY_DIRECTOR
Name: Omar H. Abdelaleem, PhD
Affiliation: Faculty pf medicine, Mansoura University
Role: PRINCIPAL_INVESTIGATOR