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Spots Global Cancer Trial Database for Effect of Parecoxib Sodium and Flurbiprofen Injection on Postoperative Shivering

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Trial Identification

Brief Title: Effect of Parecoxib Sodium and Flurbiprofen Injection on Postoperative Shivering

Official Title: Tumor Hospital of Guangxi Medical University, China

Study ID: NCT02569905

Study Description

Brief Summary: Shivering is an early postoperative complication during the postoperative recovery period, and there is no clear consensus about the best way for its prevention. The aim of the study was to compare the efficacy and accompanying side effects of prophylactic flurbiprofen with that of parecoxib or placebo for reducing postoperative shivering.

Detailed Description: 154 patients with American Society of Anesthesiologists physical status I-II, who were scheduled for colorectal operation under general anesthesia, were randomly assigned to receive flurbiprofen (Group F), parecoxib sodium (Group P ) or normal saline(Group S)40min before the end of surgery. Hemodynamic parameters were monitored. The occurrence of shivering postoperative nausea and vomiting were recorded during the recovery period. And visual analogue score (VAS) and ramsy sedation scale (RSS) were also recorded.

Eligibility

Minimum Age: 21 Years

Eligible Ages: ADULT

Sex: ALL

Healthy Volunteers: Yes

Locations

Anesthesia Department, Tumor Hospital of Guangxi Medical University, Nanning, Guangxi, China

Contact Details

Useful links and downloads for this trial

Clinicaltrials.gov

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