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Spots Global Cancer Trial Database for New Prognostic and Predictive Biomarkers for HPV-associated Oropharyngeal Cancer

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Trial Identification

Brief Title: New Prognostic and Predictive Biomarkers for HPV-associated Oropharyngeal Cancer

Official Title: New Prognostic and Predictive Biomarkers for HPV-associated Oropharyngeal Cancer

Study ID: NCT06097936

Study Description

Brief Summary: The study involves the coexistence of a retrospective part, in which a group of patients with HPV-associated OPC for whom follow-up data of at least 2 years after diagnosis are available, designed in order to evaluate the expression of HPV16-specific E5 transcript as well as that of pEGFR and HLA, and a multicenter prospective part, involving the enrollment of a control group, enrolled at the ENT outpatient clinic of the IRE and the outpatient clinics of the relevant LILT provincial committees, to better elucidate the role of HPV16-E5 in identifying potentially transforming infections due to the presence of HPV.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: MALE

Healthy Volunteers: Yes

Locations

"Regina Elena" National Cancer Institute, Rome, , Italy

Contact Details

Useful links and downloads for this trial

Clinicaltrials.gov

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